Clinical Trials in Minneapolis

Showing 9221-9240 of 11,007 trials

Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants

NCT00004410

OBJECTIVES: I. Determine whether infants treated with tauroursodeoxycholic acid (TUDCA) have a lower peak direct bilirubin, ALT, AST, glutamyltranspeptidase levels and a reduced duration of cholestasis compared to the nontreatment arm. II. Determine the significance of lower birth weight and longer duration of total parenteral nutrition (TPN) on increasing risk of TPN associated cholestasis and increasing benefit from TUDCA therapy. III. Determine whether TUDCA therapy leads to significant reduction in the appearance of biliary tract sludge and/or stone formation in these infants. IV. Determine whether TUDCA therapy leads to reduced urinary excretion of potentially hepatotoxic bile acids as compared to the untreated arm matched for birth weight and duration of TPN.

Cholestasis

Children's Hospital Medical Center, Cincinnati50 participantsStarted Jun 1998

Minneapolis, Minnesota, United States • Jackson, Mississippi, United States • Cincinnati, Ohio, United States

TERMINATEDPhase 2/3< 1 mile

Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis

NCT00430677

The purpose of this clinical research study is to learn if addition of abatacept is safe and improves the effectiveness of treatment of patients with active lupus nephritis who are also taking mycophenolate mofetil (MMF) and corticosteroids.

Systemic Lupus Erythematosus

Bristol-Myers Squibb423 participantsStarted Jun 2007

Birmingham, Alabama, United States • Tucson, Arizona, United States • Los Angeles, California, United States +81 more locations

Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants

Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis

Find Trials by Condition in Minneapolis

Dialysis Clinical Outcomes Revisited (DCOR) Trial

Open Label Dose Escalation Phase I Study to Investigate the Safety and Pharmacokinetics of T121E01F and T121E02F in Healthy Postmenopausal Women

Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery

Healthy Homes/Healthy Kids_5-9

An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes

Acupuncture for Pain Management After Hip or Knee Arthroplasty

Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)

Clinical Investigation of Expanded Designs of a Multifocal IOL

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Patient-Reported Outcomes in Adults With Congenital Heart Disease

Rituximab in Renal Allograft Recipients Who Develop Early De Novo Anti-HLA Alloantibodies

Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis

A Phase 4, Conversion Study of Hectorol® Injection to Hectorol® Capsules in Stage 5 CKD Patients on Dialysis

BB-10901 in Treating Patients With Relapsed or Refractory Solid Tumors

A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women

Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme

Fibroid Ablation Study - Large Fibroids