Clinical Trials in Michigan

Showing 1981-2000 of 7,755 trials

AVID100 in Advanced Epithelial Carcinomas

NCT03094169

Approximately 90 male and female patients with documented solid tumor malignancies of epithelial origin that are locally advanced or metastatic, and either refractory to standard therapy or for whom no standard therapy is available, will be entered into this Phase 1a/2a, multicenter, open-label, dose-escalation, cohort study of AVID100. Phase 2a will include evaluation of patient with EGFR-overexpressing squamous histology non-small cell lung cancer, squamous cell carcinoma of the head and neck, and triple negative breast cancer

Solid Tumor, AdultTriple Negative Breast CancerHead and Neck Squamous Cell Carcinoma+1 more

Formation Biologics49 participantsStarted Feb 2017

New Haven, Connecticut, United States • Grand Rapids, Michigan, United States • New York, New York, United States +7 more locations

TERMINATED83 miles

Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3

NCT03278873

This is a longer-term follow-up study of patients with achromatopsia associated with defects in CNGA3 who participated in a clinical trial in which they received AAV-CNGA3 retinal gene therapy, or of patients with achromatopsia associated with defects in CNGB3 who participated in a clinical trial in which they received AAV-CNGB3 retinal gene therapy.

Achromatopsia

MeiraGTx UK II Ltd34 participantsStarted Jun 2017

Ann Arbor, Michigan, United States • London, United Kingdom

AVID100 in Advanced Epithelial Carcinomas

Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3

Find Trials by Condition in Michigan

Validation of a Multi-gene Test for Lung Cancer Risk

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Metastatic Castrate-Resistant Prostate Cancer

Follow-up of the EPITOPE Study to Evaluate Long-term Efficacy and Safety of DBV712 in Young Children

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

TAC T-cells for the Treatment of HER2-positive Solid Tumors

ProVIDE II Bridging Study

Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6

A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease

An Evaluation of the Safety of CSF-1 in Presbyopic Subjects

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies

Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections

A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma