Clinical Trials in Miami

Showing 4081-4100 of 11,431 trials

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

NCT03604783

TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib. This is a Phase 1, open-label, dose-escalation, dose-expansion, safety, pharmacokinetics, and pharmacodynamic study, with a purpose of determining the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of oral TP-1287 in patients with advanced metastatic or progressive solid tumors who are refractory to, or intolerant of, established therapy known to provide clinical benefit for their condition.

Advanced Solid TumorsSarcomaEwing Sarcoma+2 more

Sumitomo Pharma America, Inc.74 participantsStarted Dec 2018

Los Angeles, California, United States • Miami, Florida, United States • Boston, Massachusetts, United States +7 more locations

COMPLETEDPhase 1< 1 mile

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST

NCT04530981

Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Substrate

GIST - Gastrointestinal Stromal Tumor

Deciphera Pharmaceuticals, LLC13 participantsStarted Sep 2021

Jacksonville, Florida, United States • Miami, Florida, United States • Portland, Oregon, United States

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST

Find Trials by Condition in Miami

Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

A Study to Compare Forms of Nemtabrutinib (MK-1026) in Healthy Adult Participants (MK-1026-007)

A Safety and Efficacy Study in Patients With Gastric Cancer

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer

Breast Cancer Index (BCI) Registry

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study of AZD9291 Plus MEDI4736 Versus AZD9291 Monotherapy in NSCLC After Previous EGFR TKI Therapy in T790M Mutation Positive Tumours

Acupuncture for Preterm Infants Requiring Eye-exam

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry