Clinical Trials in Massachusetts

Showing 1801-1820 of 8,511 trials

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

NCT02614547

This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the efficacy, safety, and pharmacokinetics of SAGE-547 Injection in adult female participants diagnosed with severe postpartum depression.

Severe Postpartum Depression

Supernus Pharmaceuticals, Inc.21 participantsStarted Dec 2015

Atlanta, Georgia, United States • Worcester, Massachusetts, United States • Chapel Hill, North Carolina, United States +1 more locations

RECRUITING14 miles

Botulinum Toxin Therapy in Hidradenitis Suppurativa

NCT05403710

This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease Hidradenitis Suppurativa (HS). In this study, the investigators will test the hypothesis that inhibiting neuropeptide activity with botulinum toxin reduces pathogenic inflammation.

Hidradenitis SuppurativaHyperhidrosis

University of Massachusetts, Worcester20 participantsStarted Jun 2022

Worcester, Massachusetts, United States

Active Not RecruitingNA21 miles

Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease

NCT04289402

The objective of this study is to conduct a pilot, randomized sham-controlled trials to determine the feasibility and effects of a 10-session personalized tDCS intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in 24 older adults with mild AD living in supportive housing.

Alzheimer DementiaPresenile Alzheimer DementiaAging

Hebrew SeniorLife11 participantsStarted Jan 2020

Roslindale, Massachusetts, United States

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

Botulinum Toxin Therapy in Hidradenitis Suppurativa

Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease

Find Trials by Condition in Massachusetts

The Use of Mentoring to Promote Well-being for Female SMART Members

Mechanisms of Open and Hidden Placebo in Stroke Recovery

Omnipod 5 System Compared to Pump Therapy

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

CP101 for the Treatment of Ulcerative Colitis

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation

A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

BlueWind RENOVA iStim™ System for the Treatment of OAB

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

Periprosthetic Fracture Registry (PPFx)

Locking Plates for Distal Femur Fractures - a Multicenter Case Review