Clinical Trials in Massachusetts

Showing 1681-1700 of 8,511 trials

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

NCT02400190

This study will collect rates of local/regional recurrence in select patients who do not receive radiation treatment after lumpectomy surgery. These women must be postmenopausal; have hormone receptor-positive, Her2-negative tumors; have Oncotype-DX RS less than or equal to 18; and plan to receive endocrine therapy. In this way, this study seeks to collect prospective data supporting the idea that this is a population at sufficiently low risk of local/regional recurrence that omission of adjuvant radiation might be a reasonable option.

Breast Neoplasms

University of Michigan Rogel Cancer Center202 participantsStarted May 2015

Stanford, California, United States • New Haven, Connecticut, United States • Maywood, Illinois, United States +10 more locations

COMPLETEDPhase 326 miles

Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

NCT06729606

This study looks at the safety and effectiveness of Aviptadil in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with Aviptadil plus current standard of care (SOC), or with placebo plus current SOC.

Covid19

National Institute of Allergy and Infectious Diseases (NIAID)471 participantsStarted Apr 2021

Tucson, Arizona, United States • Fresno, California, United States • Loma Linda, California, United States +37 more locations

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

Find Trials by Condition in Massachusetts

A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

The COMPASSION Study

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

Improving Outcomes Assessment in Chronic GVHD

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

VItamin C in Thermal injuRY: The VICToRY Trial

Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD

Efficacy and Safety of Tisagenlecleucel in Adult Patients With Refractory or Relapsed Follicular Lymphoma

Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma

A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy

Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection