Clinical Trials in Massachusetts

Showing 15441-15460 of 17,868 trials

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

NCT00535821

Early intervention in the treatment of septic shock, including early goal-directed therapy (EGDT) in the first 6 hours of disease presentation, has been shown to significantly decrease mortality. However, this approach requires invasive hemodynamic monitoring, thus limiting its widespread application in the emergency department setting. A minimally invasive protocol utilizing esophageal Doppler monitoring (EDM) may be of benefit and practical if it is shown to result in similar outcome as EGDT.

Severe SepsisSeptic Shock

Loma Linda University5 participantsStarted Jun 2007

Loma Linda, California, United States • Loma Linda, California, United States • Worcester, Massachusetts, United States +1 more locations

COMPLETEDPhase 214 miles

AST-120 Used to Treat Mild Hepatic Encephalopathy

NCT00867698

The purpose of this study is to determine whether AST-120 is safe and effective in the treatment of mild hepatic encephalopathy.

Mild Hepatic Encephalopathy

Ocera Therapeutics148 participantsStarted Mar 2009

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Fresno, California, United States +35 more locations

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

AST-120 Used to Treat Mild Hepatic Encephalopathy

Find Trials by Condition in Massachusetts

Predicting Cognitive Resilience Against Sleep Loss

Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia

Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia

Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT Device

Effectiveness and Safety Study for JNJ-18054478 in Asthma Patients.

A Study of Ramucirumab in Participants With Metastatic Renal Cell Carcinoma

Implementing a Comprehensive Handoff Program to Improve Patient Safety

Respimat® Combivent Trial in Chronic Obstructive Pulmonary Disease (COPD)

Cisplatin, Irinotecan, and Bevacizumab, in Treating Patients With Small Cell Lung Cancer

Dose Range Finding Study of Fedovapagon in Men With Nocturia

Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies

Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes

A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines

Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome

Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension

A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder

A Study of IMC-1121B (Ramucirumab) in Colorectal Cancer

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV