Clinical Trials in Massachusetts

Showing 12481-12500 of 15,316 trials

A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Patients With Infantile-Onset Pompe Disease

NCT01597596

A study to demonstrate comparable safety, efficacy, and pharmacokinetics (PK) of alglucosidase alfa manufactured at the 160 litre (L) and 4000 L scales in participants who had been diagnosed with infantile-onset Pompe disease. Participants were treated with alglucosidase alfa 160 L scale product in the United States (US) and 4000 L scale product in the regions outside the US.

Pompe Disease (Infantile-Onset)Glycogen Storage Disease Type II (GSD II)Glycogenosis 2+1 more

Genzyme, a Sanofi Company4 participantsStarted Aug 2012

Little Rock, Arkansas, United States • Oakland, California, United States • Gainsville, Florida, United States +14 more locations

TERMINATEDPhase 226 miles

Study of Renal Denervation in Patients With Heart Failure

NCT01954160

Congestive heart failure is a common disorder in which the heart cannot pump enough blood to meet the needs of the rest of the body. Poor sodium handling by the kidneys is a damaging effect of heart failure, and it leads to symptoms of congestion such as shortness of breath or ankle swelling. Recent studies suggest that reducing the nerve activity to a kidney could reduce sodium retention and blood pressure. An improvement in the way the kidneys handle sodium may reduce disease progression and decrease symptoms for heart failure patients.

Heart Failure

Adrian Hernandez5 participantsStarted Dec 2013

Atlanta, Georgia, United States • Boston, Massachusetts, United States • Boston, Massachusetts, United States +9 more locations

A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Patients With Infantile-Onset Pompe Disease

Study of Renal Denervation in Patients With Heart Failure

Find Trials by Condition in Massachusetts

Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients

JC Virus Reactivation in Multiple Sclerosis

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanoma

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Abatacept in Treating Adults With Mild Relapsing Wegener's Granulomatosis

Improving Management of Outpatient Actionable Test Results

A Novel Motivational Ecological Momentary Intervention for Anorexia Nervosa

A Study To Assess The Efficacy And Safety Of PF-04236921 In Subjects With Crohn's Disease Who Failed Anti-TNF Therapy

Tiotropium+Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 2)

Safety and Tolerability of Glatiramer Acetate

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1

Study of How Dulaglutide Compares to Placebo in Participants With Type 2 Diabetes Who Are Also on Sulfonylurea Therapy (AWARD-8)

Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome

Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)

Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib

Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer

104RA204 Assessment of the Safety and Efficacy of BG9924 in Rheumatoid Arthritis (RA) Participants