Clinical Trials in Massachusetts

Showing 9781-9800 of 17,868 trials

Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure

NCT04359082

The primary purpose is to test whether cocoa-rich bioflavanols can improve blood flow to the hand and fingers and improve hand function/dexterity during cold exposure. Secondary purpose is to understand whether bioflavanol supplementation can change the gut microbiome.

Cold ExposureManual DexterityGut Microbiome

United States Army Research Institute of Environmental Medicine40 participantsStarted Jan 2020

Natick, Massachusetts, United States

COMPLETEDPhase 214 miles

Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration

NCT02510794

This is a Phase II multicenter, dose-ranging, randomized, active treatment (monthly ITV injection)-controlled study to evaluate the efficacy, safety, and pharmacokinetics of ranibizumab delivered through the Implant using three ranibizumab formulation arms (10 mg/mL, 40 mg/mL, and 100 mg/mL) compared with the control arm (0.5-mg monthly ITV injections of 10-mg/mL formulation) in participants with subfoveal neovascular age-related macular degeneration (nAMD).

Macular Degeneration

Genentech, Inc.225 participantsStarted Sep 2015

Mesa, Arizona, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +47 more locations

Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure

Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration

Find Trials by Condition in Massachusetts

Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression

Clinical Decision Support Tools for Antibiotic Prescribing

Safety of Inhaled Hydrogen Gas Mixtures in Healthy Volunteers

Assessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC)

The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit

Vitamin D Status in Patients With Severe Sepsis

Autologous Fecal Microbiota Transplantation to Prevent Antibiotic Resistant Bacteria Colonization

A Feasibility Study to Assess the Use of Gadolinium in Computed Tomography

Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.

Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis

DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2

A Study of JNJ-64304500 in Participants With Alopecia Areata

Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis

Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Tracheal Occlusion To Accelerate Lung Growth (TOTAL) Trial for Severe Pulmonary Hypoplasia

A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors