Clinical Trials in Massachusetts

Showing 9021-9040 of 17,868 trials

The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign

NCT04644328

Facebook ads with physician-delivered videos were shown before the Thanksgiving and Christmas holidays and focused on staying safe during the COVID pandemic by limiting travel and mask-wearing.

Covid19

National Bureau of Economic Research, Inc.820 participantsStarted Nov 2020

Cambridge, Massachusetts, United States

COMPLETEDPhase 326 miles

A Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

NCT03559699

Study AG348-C-007 was a multicenter study designed to evaluate the efficacy and safety of treatment with AG-348 in a minimum of 20, with up to 40, participants with pyruvate kinase (PK) deficiency, who were regularly receiving blood transfusions. The study was composed of two parts. During Part 1, Dose Optimization Period, participants started on a dose of 5 mg AG-348 administered twice daily. Over the course of Part 1 each participant's dose of AG-348 was sequentially increased to 20 mg twice a day, followed by 50 mg twice a day depending on their tolerance. During Part 2, Fixed-Dose Period, participants received AG-348 at their optimized dose from Part 1.

Pyruvate Kinase DeficiencyAnemia, Hemolytic

Agios Pharmaceuticals, Inc.27 participantsStarted Jun 2018

Oakland, California, United States • Atlanta, Georgia, United States • Boston, Massachusetts, United States +16 more locations

The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign

A Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Find Trials by Condition in Massachusetts

A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapy

Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva

COBRA PZF™ Coronary Stent for Early Healing, Thrombus Inhibition, Endothelialization and Avoiding Long-Term DAPT

A Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors

Efficacy Study of Oral Seliciclib to Treat Non-Small Cell Lung Cancer

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 03

Social Media Indoor Tanning Study

The RE-ENERGIZE Study: RandomizEd Trial of ENtERal Glutamine to minimIZE Thermal Injury

A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)

Brodalumab (AMG 827) in Adults With Moderate to Severe Crohn's Disease

Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

Trial Comparing Adjuvant Chemotherapy With Gemcitabine Versus mFolfirinox to Treat Resected Pancreatic Adenocarcinoma

Efficacy, Safety and Tolerability of PF-06687234 as Add-on Therapy to Infliximab in Active UC Subjects Not in Remission.

Comic Intervention for Sexual Violence Prevention and Post-rape Care

Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders

A Study to Assess Safety, Tolerability, and Immunogenicity of V591 (COVID-19 Vaccine) in Healthy Participants (V591-001)