Clinical Trials in Massachusetts

Showing 8141-8160 of 17,868 trials

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

NCT03842436

This study deploys a novel digital pill with Emtricitabine/Tenofovir (TDF/FTC) among MSM with substance use to monitor PrEP adherence. The investigators will enroll N=15 HIV uninfected MSM with self reported substance use who are on PrEP or initiating PrEP to use digital pills over encapsulating TDF/FTC for 3 months. The investigators will assess the feasibility of using digital pills in this study population as well as understand the acceptability of digital pills for adherence measurement using semi-structured individual interviews. Additionally, the investigators will measure adherence over time, as well as episodes of suboptimal PrEP adherence.

HIV/AIDSSubstance Use DisordersAdherence, Medication

Brigham and Women's Hospital16 participantsStarted Oct 2018

Boylston, Massachusetts, United States

TERMINATEDPhase 326 miles

Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI

NCT02352753

This is a prospective, multicenter, single-arm study in children 2 to 17 years of age with OI to evaluate efficacy and safety of denosumab.

Osteogenesis Imperfecta

Amgen153 participantsStarted Jun 2015

Los Angeles, California, United States • Torrance, California, United States • Aurora, Colorado, United States +46 more locations

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI

Find Trials by Condition in Massachusetts

REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects

Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Without A Recent History of Blood Transfusion

Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D

Electronic Symptom Monitoring Intervention for Hospitalized Patients With Cancer

An Investigational Study to Evaluate Experimental Medication BMS-986165 Compared to Placebo and a Currently Available Treatment in Participants With Moderate-to-Severe Plaque Psoriasis

VIBRANT Study of Vurolenatide in Adult Patients With Short Bowel Syndrome.

A Study Evaluating the Efficacy of Venetoclax Plus Ibrutinib in Participants With T-cell Prolymphocytic Leukemia

Initiating and Maintaining Physical Activity in Depressed Individuals

Wellness for 2: Understanding How to Foster Well Being for Mom and Her Baby

Bag Mode BreathID Hp Validation Versus Endoscopy in Detection of Helicobacter Pylori

An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus

Assessing Portal Hypertension With Methacetin Breath Test

A Research Study Looking at How a Factor VIII Medicine Called Turoctocog Alfa Pegol (N8-GP) Works in People With Haemophilia A

Exalenz Lab Mode System Compared to Biopsy for H.Pylori Detection

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Prediction Value of the BreathID 13C-Methacetin Breath Test for Hepatic Decompensation

A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics