Clinical Trials in Massachusetts

Showing 7721-7740 of 13,570 trials

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

NCT03139331

This is the first study to evaluate the safety and clinical activity of the combination of oral pazopanib, intravenous or oral irinotecan, and oral temozolomide in pediatric and young adult patients with relapsed or refractory sarcomas. This study will use a 3 + 3 design for dose escalation (Part 1), followed by an expansion cohort (Part 2) at the recommended phase 2 dose level.

SarcomaRefractory Sarcoma

University of California, San Francisco16 participantsStarted Jun 2017

Oakland, California, United States • San Francisco, California, United States • Boston, Massachusetts, United States

COMPLETEDPhase 1/226 miles

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

NCT00621244

This study evaluated safety, tolerability, pharmacokinetics and preliminary anti-leukemic or anti-tumor activity of LBH589B in adult patients with advanced hematological malignancies

LymphomaLeukemiaMultiple Myeloma

Novartis Pharmaceuticals175 participantsStarted Mar 2003

Augusta, Georgia, United States • Boston, Massachusetts, United States • Houston, Texas, United States +4 more locations

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Find Trials by Condition in Massachusetts

Dose Range Finding Study of Bimagrumab in Sarcopenia

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies

Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza

Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes

Safety, Tolerability, and Efficacy of BVS857 in Patients With Spinal and Bulbar Muscular Atrophy

Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients

ACZ885 for the Treatment of Abdominal Aortic Aneurysm

Efficacy and Safety Study of CSJ148 in Stem Cell Transplant Patients

Efficacy and Safety of LFG316 in Transplant Associated Microangiopathy (TAM) Patients

Korean Medicine for Symptomatic Lumbar Spinal Spondylolisthesis