Clinical Trials in Massachusetts

Showing 6461-6480 of 17,868 trials

A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

NCT06225973

In this prospective, phase 2b, multicenter, randomized, double-masked, vehicle-controlled, parallel-arm study, approximately 880 subjects with moderate to severe dry eye disease (DED) will be randomly assigned (1:1) to receive either TL-925 or vehicle as topical ophthalmic eye drops administered bilaterally BID. The study will comprise two phases: a two-week screening phase/run-in and a six-week double-masked treatment phase.

Dry Eye Disease

Telios Pharma, Inc.880 participantsStarted Feb 2024

Phoenix, Arizona, United States • Glendale, California, United States • La Mesa, California, United States +15 more locations

TERMINATEDPhase 326 miles

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

NCT02914600

The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior filgotinib treatment study in Crohn's disease (CD).

Crohn's Disease

Galapagos NV1,188 participantsStarted Mar 2017

Dothan, Alabama, United States • Sun City, Arizona, United States • Coronado, California, United States +483 more locations

A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

Find Trials by Condition in Massachusetts

Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders

Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD

Confirmation of Diet as a Treatment for Gulf War Illness

Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

A Clinical Safety Study of AT-100 (rhSP-D) in Preterm Neonates at High Risk for Bronchopulmonary Dysplasia (BPD)

Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

TARGET Post-Approval Study

An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease

Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer

Evaluate the Efficacy and Safety of TGR-1202 in Participants With Chronic Lymphocytic Leukemia Who Are Intolerant to Prior Therapy

IPG Replacement Study (PREFERENCE-H)

A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop

A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)

Clinical Evaluation of the FilmArray® Global Fever (GF) Panel

A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT

Study of AMG 160 in Subjects With Non-Small Cell Lung Cancer

Short-term Preoperative Treatment With Enzalutamide, Alone or in Combination With Exemestane in Primary Breast Cancer