Clinical Trials in Massachusetts

Showing 6301-6320 of 17,868 trials

Study of Clinic-delivered Physical Activity Referrals to Cancer Survivors

NCT05216380

Background: Cancer survivors have a greater risk of cardiovascular disease (CVD) and have low physical activity levels. Physical inactivity is one modifiable risk factor for CVD, and increased physical activity has shown a cardioprotective effect on lowering CVD risk. The objective of ActivityLink is to use an electronic referral (e-referral) implementation program for clinic staff to refer survivors to an in-person and a virtual physical activity program. Methods: Participants in this study will include clinic staff and patients. Investigators will first conduct interviews with clinic staff and patients, followed by usability testing of a referral system with staff. The study team will then beta-test two rounds of testing using Plan, Do, Study, Act (PDSA) Cycles for clinic staff to refer patients in the clinic. Quantitative data and qualitative interviews will be collected following each PDSA cycle, with refinements made based on feedback. Outcomes: The proposed study addresses a critical need to implement physical activity referrals into routine cancer survivorship visits.

CancerPhysical Inactivity

University of Massachusetts, Worcester69 participantsStarted Mar 2021

Worcester, Massachusetts, United States

RECRUITINGNA26 miles

Neural Mechanisms of Family-Focused Treatment for Youth Depression

NCT06289010

The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it aims to answer are: * What are differences between depressed and non-depressed participants on baseline neural and parenting indicators? * Do baseline neural and parenting indicators predict response to FFT-CD? * Does change in parenting and neural functioning mediate change in depression from baseline to follow-up? Participants will: * complete baseline clinical measures * complete neuroimaging tasks via Functional Magnetic Resonance Imaging (fMR) * undergo a 12-session course of FFT-CD * complete follow up evaluations and neuroimaging

Childhood Depression

Boston University Charles River Campus80 participantsStarted Aug 2024

Boston, Massachusetts, United States • Charlestown, Massachusetts, United States

Study of Clinic-delivered Physical Activity Referrals to Cancer Survivors

Neural Mechanisms of Family-Focused Treatment for Youth Depression

Find Trials by Condition in Massachusetts

A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator

Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer

TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)

Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care

Autoantibody Reduction Therapy in Patients With Idiopathic Pulmonary Fibrosis

Vaccination With Autologous, Lethally Irradiated Melanoma Cells Engineered by Adenoviral Mediated Gene Transfer to Secrete Granulocyte-Macrophage Stimulating Factor (GMSF)

Personalizing Intervention to Reduce Clinical Inertia in the Treatment of Hypertension

A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)

Clinical Evaluation of the Infinity Deep Brain Stimulation System

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

A Study of Orally Administered JBPOS0101 in Refractory Infantile Spasms Patients

A Study of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Diphtheria, Pertussis and Tetanus (Tdap) Viruses Followed by a 2nd Dose of the RSV Vaccine to Healthy Non-Pregnant Women

Effects of EDP-938 in Hematopoietic Cell Transplant Recipients Infected With Respiratory Syncytial Virus of the Upper Respiratory Tract

COLOR II: Laparoscopic Versus Open Rectal Cancer Removal

Medtronic HAMMOCK Post Approval Study