Clinical Trials in Massachusetts

Showing 6141-6160 of 13,570 trials

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

NCT03842436

This study deploys a novel digital pill with Emtricitabine/Tenofovir (TDF/FTC) among MSM with substance use to monitor PrEP adherence. The investigators will enroll N=15 HIV uninfected MSM with self reported substance use who are on PrEP or initiating PrEP to use digital pills over encapsulating TDF/FTC for 3 months. The investigators will assess the feasibility of using digital pills in this study population as well as understand the acceptability of digital pills for adherence measurement using semi-structured individual interviews. Additionally, the investigators will measure adherence over time, as well as episodes of suboptimal PrEP adherence.

HIV/AIDSSubstance Use DisordersAdherence, Medication

Brigham and Women's Hospital16 participantsStarted Oct 2018

Boylston, Massachusetts, United States

TERMINATEDNA26 miles

Trial on Endovascular Aneurysm Management

NCT00537134

The management of patients with unruptured aneurysms is controversial. Patients with unruptured aneurysms may suffer intracranial hemorrhage, but the incidence of this event is still debated. Endovascular treatment can prevent rupture, but involves immediate risks; furthermore, successful treatment does not eliminate all risks. A randomized trial may be the best way to demonstrate the potential benefits of endovascular over conservative management of unruptured aneurysms.

Brain Aneurysm

Centre hospitalier de l'Université de Montréal (CHUM)80 participantsStarted Apr 2006

Phoenix, Arizona, United States • Boston, Massachusetts, United States • Brooklyn, New York, United States +6 more locations

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

Trial on Endovascular Aneurysm Management

Find Trials by Condition in Massachusetts

Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement

Addition of X4P-001 to Nivolumab Treatment in Participants With Renal Cell Carcinoma

OLAParib COmbinations

Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI

REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects

A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Without A Recent History of Blood Transfusion

Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Electronic Symptom Monitoring Intervention for Hospitalized Patients With Cancer

Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D

An Investigational Study to Evaluate Experimental Medication BMS-986165 Compared to Placebo and a Currently Available Treatment in Participants With Moderate-to-Severe Plaque Psoriasis

Neuromodulation of Lidocaine Cream Effect on Chronic Pain Patients

Wellness for 2: Understanding How to Foster Well Being for Mom and Her Baby

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma

A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of Age

A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics

A Rollover Study to Provide Continued Treatment With Eltrombopag