Clinical Trials in Massachusetts

Showing 5901-5920 of 13,570 trials

Novel Use of Restasis and PROSE Devices

NCT04735510

The goal of this prospective observational pilot study is to evaluate the tolerability and safety of RESTASIS (cyclosporine ophthalmic solution 0.05%) when added to the PROSE (Prosthetic Replacement of the Ocular Surface Ecosystem) lens reservoir in patients with ocular surface disease (OSD).

Ocular Surface Disease

Boston SightStarted May 2021

Needham, Massachusetts, United States

COMPLETEDNA26 miles

MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms

NCT04231097

Brief Summary: The aim of this study is to explore the initial feasibility and acceptability of (a) Mindfulness-Based Cognitive Therapy (MBCT) adapted for ACS patients; (b) the group videoconferencing delivery medium; and (c) dried blood spot research procedures, to inform refinements for a subsequent pilot RCT.

Acute Coronary SyndromeDepressionMyocardial Infarction+3 more

Massachusetts General Hospital8 participantsStarted Apr 2020

Boston, Massachusetts, United States

COMPLETEDPhase 126 miles

Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults

NCT02296541

The purpose of this study is to evaluate the safety and immune response to three DNA vaccines and a MVA-CMDR vaccine that may boost the immune response to the DNA vaccines in healthy, HIV-uninfected adults.

HIV Infections

National Institute of Allergy and Infectious Diseases (NIAID)105 participantsStarted Dec 2014

Birmingham, Alabama, United States • San Francisco, California, United States • Decatur, Georgia, United States +4 more locations

Novel Use of Restasis and PROSE Devices

MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms

Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults

Find Trials by Condition in Massachusetts

Molecular Analysis of Patients With Neuromuscular Disease

Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle

A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

Trauma Informed Intervention to Support Engagement in HIV Care Among MSM (THRIVE+)

Genomic Response Analysis of Heart Failure Therapy in African Americans

The Effect of Fontan Fenestration Closure on Hepatic Stiffness

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer

Safety and Effectiveness of BioTraceIO Lite for Tissue Damage Assessment Following Liver Tissue Ablation Procedures

Step Into Support for Endurance and Strength (SISTERS)

Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)

VERU-111 in the Treatment of SARS-Cov-2 Infection by Assessing Its Effect on the Proportion of Patients Who Die on Study

A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)

Efficacy and Safety Study of Satralizumab (SA237) as Add-on Therapy to Treat Participants With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD)