Clinical Trials in Massachusetts

Showing 5281-5300 of 13,570 trials

Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

NCT03337620

This is a double blind placebo-controlled study which will evaluate the efficacy of bupivacaine compared to saline, delivered by the Tx360® device to the sphenopalatine ganglion (SPG), to treat chronic migraine headache. The Tx360® is a nasal applicator which is cleared through the FDA for transnasal medication delivery, including delivery to the SPG. The SPG has been implicated in a variety of cephalalgias. It is critical to the success of this intervention that the blocking agent be accurately delivered to this area as it is the only non-bony access to the pterygopalatine fossa (PPF). Subjects meeting inclusion/exclusion criteria will receive 12 intranasal treatments to the SPG over a period of 4 weeks with follow-up monthly for an additional 3 months post-treatment.

Headache, Migraine

Tian Medical Inc.174 participantsStarted Sep 2017

New Haven, Connecticut, United States • Stamford, Connecticut, United States • Fort Gordon, Georgia, United States +8 more locations

UNKNOWNNA21 miles

Electronic Cigarettes and Reactivity to Smoking Cues

NCT01782599

The purpose of this study is to determine whether electronic cigarettes can reduce reactivity to smoking-related cues.

Nicotine Dependence

Mclean Hospital125 participantsStarted Jan 2013

Belmont, Massachusetts, United States

Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

Electronic Cigarettes and Reactivity to Smoking Cues

Find Trials by Condition in Massachusetts

A Study of OV101 in Individuals With Angelman Syndrome (AS)

Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

A Study of PTC923 in Participants With Phenylketonuria

Time-restricted Eating in Peri- and Postmenopausal Women

A Post-Approval Study of the LINX® Reflux Management System

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

Evaluation of Immunobiogram® as a Tool in Adjustment of Immunosuppressant Therapy for Renal Transplant

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium.

Development of a Questionnaire to Evaluate Patient Expectations for Breast Reconstruction in Women With Breast Cancer or Other Conditions

A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer

Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System

Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)

Diffusion-Weighted MRI for Liver Metastasis

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19

International REACH Forgiveness Intervention