Clinical Trials in Massachusetts

Showing 5181-5200 of 17,868 trials

Study of REM-422 in Patients With AML or Higher Risk MDS

NCT06297941

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with Higher Risk MDS and relapsed/refractory AML

Myelodysplastic SyndromesHigher Risk Myelodysplastic SyndromesAcute Myeloid Leukemia+1 more

Remix Therapeutics100 participantsStarted Apr 2024

Duarte, California, United States • Tampa, Florida, United States • Boston, Massachusetts, United States +6 more locations

COMPLETEDNA26 miles

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System

NCT05120193

This is a prospective, multicenter, randomized clinical evaluation of the Sphere-9 Mapping and Ablation Catheter with the Affera Mapping and Ablation System. Subjects will be randomly assigned 1:1 to receive treatment with either the Sphere-9 Mapping and Ablation Catheter and the Affera Mapping and Ablation System (investigational device) or the THERMOCOOL SMARTTOUCH® SF radiofrequency ablation catheter (control device).

Atrial Fibrillation

Medtronic Cardiac Ablation Solutions477 participantsStarted Dec 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Jonesboro, Arkansas, United States +20 more locations

Study of REM-422 in Patients With AML or Higher Risk MDS

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System

Find Trials by Condition in Massachusetts

Mixed Vs Blocked Search: Four Unique Tasks

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)

FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer

A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma

Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts

Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder

AZD7442 Pharmacokinetics, Pharmacodynamics, and Safety Evaluation in Pediatrics

Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis

A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macular Edema

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma