Clinical Trials in Massachusetts

Showing 3961-3980 of 11,623 trials

A Retrospective Review Evaluating the Matrix Pro Applicator for Treatment of Wrinkles

NCT06219278

This is a retrospective chart review of data from the multi-site prospective clinical trial, "Functional Usability and Feasibility Testing of the Profound Matrix™ System (FUFT2002)" to evaluate the safety and efficacy of the Profound Matrix System Matrix Pro applicator for the treatment of wrinkles.

Wrinkle

Candela Corporation32 participantsStarted Oct 2023

Marlborough, Massachusetts, United States • Yokneam Illit, Israel

COMPLETEDPhase 314 miles

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

NCT05033080

The purpose of this study evaluates the efficacy and safety of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants who were heterozygous for F508del and a minimal function mutation (F/MF participants).

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated435 participantsStarted Sep 2021

Birmingham, Alabama, United States • Tucson, Arizona, United States • Little Rock, Arkansas, United States +136 more locations

A Retrospective Review Evaluating the Matrix Pro Applicator for Treatment of Wrinkles

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Find Trials by Condition in Massachusetts

Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment

Study of the Associations Between Subchondral Insufficiency Fractures of the Knee and Pre-existing Health, Lifestyle, and/or Musculoskeletal Conditions

Burden of Nintedanib Non-adherence Among Idiopathic Pulmonary Fibrosis (IPF) Patients

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force

Post-Market Study to Assess Outcomes of Patients Treated With AFX System Compared to Other EVAR Devices

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Open-Label Extension Study of Trofinetide for Rett Syndrome

Observational Study of Obstructive Lung Disease (NOVELTY)

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With Other Antiretroviral Agents in People Living With HIV

Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)

A Study to Learn About The Study Medicine (PF-07038124) In Patients With Mild To Moderate Atopic Dermatitis Or Mild To Severe Plaque Psoriasis.

Assessment of 3M Oedema Reduction System in the Treatment of Lymphoedema Compared to Commercial Short-stretch Bandage

Alleviate-HF-2 Study

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in Remission

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors