Clinical Trials in Massachusetts

Showing 2121-2140 of 8,511 trials

A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients

NCT05725018

To evaluate and further characterize the safety of EB-101 (LZRSE-Col7A1 gene-corrected keratinocyte sheets with type VII collagen \[C7\] expression) for the treatment of large, chronic DEB wounds in new and previously EB-101 treated patients 12 months and older.

Epidermolysis BullosaRecessive Dystrophic Epidermolysis BullosaRDEB

Abeona Therapeutics, Inc12 participantsStarted Apr 2023

Redwood City, California, United States • Worcester, Massachusetts, United States

Active Not RecruitingPhase 320 miles

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain

NCT05037123

The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain. Participants randomized to the first arm will receive a 0.35 mg/kg dose after induction, followed by a 0.25 mg/kg/hr infusion during surgery (up to a maximum of 6 hours) and continued for 2 hours postoperatively. Participants in the second arm will receive a single dose of 0.6 mg/kg of ketamine in the post-anesthesia care unit, and the final group will serve as the control group and receive saline (no ketamine).

Chronic Postsurgical Pain

NYU Langone Health765 participantsStarted Jan 2022

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Chicago, Illinois, United States +11 more locations

A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain

Find Trials by Condition in Massachusetts

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Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2

Gluten Technology and Education for Celiac Health

DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Hypofractionated Stereotactic Body Radiation Therapy as a Boost to the Prostate

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

Dropless Pars Plana Vitrectomy Study

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention

Impact of Self-directed Goals for Long-term Patients in a Forensic Hospital: A Mixed-Methods Pilot Study

Trial to Evaluate the Safety and Pharmacokinetics of HMPL-689 in Patients With Lymphomas

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Cough Reduction in IPF With Nalbuphine ER

Pivotal Study of the Vienna Transcatheter Self Expandable Aortic Valve SE System