Clinical Trials in Maryland

Showing 16441-16460 of 23,284 trials

Phase 1 Safety and Immunogenicity of Meningococcal Vaccine

NCT00678652

The purpose of this study is to determine whether a vaccine based on outer membrane vesicles (NOMV) from genetically detoxified group B meningococcus is safe and effective for use as a vaccine. If so, the NOMV in this vaccine will be combined with NOMV from two other genetically modified strains as a potentially globally effective vaccine against group B meningococcus.

Meningococcal Infection, Group B

U.S. Army Medical Research and Development Command36 participantsStarted Apr 2008

Silver Spring, Maryland, United States

COMPLETEDNA15 miles

Lifting and Tightening of the Face in Subjects With Skin of Darker Color

NCT01368965

This prospective, multi-center, single treatment clinical trial evaluates the clinical outcomes associated with non-invasive treatment to obtain lift and tightening of facial tissue and improve jawline definition in subjects with darker skin color utilizing the Ulthera® System to deliver focused ultrasound energy below the skin surface.

Facial Skin Laxity

Ulthera, Inc54 participantsStarted Mar 2011

Chevy Chase, Maryland, United States • Rockville, Maryland, United States

COMPLETEDPhase 217 miles

Podocyte Retinoids

NCT00098020

This is a pilot study of retinoids for patients with unsatisfactory response to conventional treatment of nephrotic syndrome due to focal segmental glomerulosclerosis or minimal change disease, two renal disorders associated with putatively pathogenic malfunctioning of glomerular podocytes. The hypothesis that retinoids may have reparative effects on these cells is based on previous research showing that retinoids promote the differentiation or redifferentiation of aberrant epithelial cells. Results obtained by 6 months of treatment with retinoids (that have been approved for non-renal indications) will be used as preliminary information upon which to base further testing of these agents in formal clinical trials in refractory cases of these nephrotic syndromes.

Collapsing GlomerulopathyGlomerulosclerosis, Focal Segmental

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)12 participantsStarted Nov 2004

Bethesda, Maryland, United States

Phase 1 Safety and Immunogenicity of Meningococcal Vaccine

Lifting and Tightening of the Face in Subjects With Skin of Darker Color

Podocyte Retinoids

Find Trials by Condition in Maryland

A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket

Study to Evaluate the Safety Tolerability and Acceptability of Long Acting Injections of the Human Immunodeficiency Virus (HIV) Integrase Inhibitor, GSK1265744, in HIV Uninfected Men (ECLAIR)

Sub-Q Versus IV Furosemide in Acute Heart Failure

Developing an Integrated Model for Home Visitation

Improving Outcomes Following Limb Loss: PALS Plus

Stitch Closure of PFO and Septal Repair

Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects Who Are Intolerant to Statins

Safety, Pharmacokinetics and Preliminary Efficacy of Asimadoline in Pruritus Associated With Atopic Dermatitis

OnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult Females

Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease

Clodronate With or Without Chemotherapy and/or Hormonal Therapy in Treating Women With Stage I or Stage II Breast Cancer

A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

International PFO Consortium

A Study of Vemurafenib in Participants With Metastatic Melanoma

HOPE Demonstration Field Experiment Multisite Evaluation

Randomized Clinical Trial Comparing 4RIF vs. 9INH for LTBI Treatment-effectiveness