Clinical Trials in Maryland

Showing 5221-5240 of 23,284 trials

CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing

NCT05130606

This is a mixed-methods Hybrid Type 1 research design (efficacy study) in which we aim to conduct a two-arm randomized controlled trial and an Implementation Focused Process Evaluation of a culturally-targeted video and referral screening tool. In this study, the investigators aim to evaluate the efficacy of a culturally targeted video previously developed by the research team vs. a Spanish-language fact sheet from an established group on enhancing genetic counseling and testing uptake and psychosocial outcomes in Latina women at risk for hereditary breast and ovarian cancer. The investigators will test the video's efficacy while also gathering data on the implementation and future sustainability of using the Risk Screening Tool (RST) and video in community clinics.

Hereditary Breast and Ovarian Cancer

Georgetown University332 participantsStarted Jun 2021

Washington D.C., District of Columbia, United States • Richmond, Virginia, United States

Active Not RecruitingPhase 317 miles

Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL

NCT02475681

This Primary objective is evaluating the efficacy of obinutuzumab in combination with chlorambucil (Arm A) compared with acalabrutinib in combination with obinutuzumab (Arm B) for the treatment of previously untreated chronic lymphocytic leukemia (CLL). Secondary objectives: 1) To evaluate the efficacy of obinutuzumab in combination with chlorambucil (Arm A) versus acalabrutinib monotherapy (Arm C) based on IRC assessment of PFS per IWCLL 2008 criteria. 2)To compare obinutuzumab plus chlorambucil (Arm A) versus acalabrutinib plus obinutuzumab (Arm B) and obinutuzumab plus chlorambucil (Arm A) versus acalabrutinib monotherapy (Arm C) in terms of: IRC-assessed objective response rate (ORR); Tine to next treatment (TTNT); Overall Survival (OS)

Chronic Lymphocytic Leukemia

Acerta Pharma BV535 participantsStarted Jun 2015

Goodyear, Arizona, United States • Phoenix, Arizona, United States • Anaheim, California, United States +152 more locations

CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing

Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL

Find Trials by Condition in Maryland

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis

Optimizing Dimensions of Reinforcement

Resiliency in U.S. Air Force Personnel

Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma

A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study

Symptom Management Implementation of Patient Reported Outcomes in Oncology

Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD

A Pilot Randomized Controlled Trial for Hand Osteoarthritis

Determination of Assay Cut-Off for the RadTox Test in Prostate Cancer Patients to Predict GI Radiation Toxicity

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Open-Label Extension Study for Subjects With H1 Antihistamine Refractory Chronic Spontaneous Urticaria Completing Study AK006-001

Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis