Clinical Trials in Maryland

Showing 501-520 of 23,284 trials

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

NCT06447025

An open label study designed to evaluate the safety, PK, PD, and clinical effects of long-term daily administration of CTI-1601 enrolling adolescent and adult patients with FRDA who have participated in a prior clinical study of CTI-1601 as well as children (age 2 years and older), adolescents and adults with FRDA who have not participated in a prior clinical study of CTI-1601.

Friedreich Ataxia

Larimar Therapeutics, Inc.85 participantsStarted Jan 2024

Los Angeles, California, United States • Gainesville, Florida, United States • Tampa, Florida, United States +5 more locations

Active Not RecruitingPhase 117 miles

Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer

NCT02298959

This phase I trial studies the side effects and best dose of ziv-aflibercept when given together with pembrolizumab in treating patients with solid tumors that that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Ziv-afibercept works by decreasing blood and nutrient supply to the tumor, which may result in shrinking the tumor. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving ziv-aflibercept together with pembrolizumab may be a better treatment for patients with advanced solid tumors.

Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Colorectal CarcinomaMetastatic Malignant Solid Neoplasm+12 more

National Cancer Institute (NCI)59 participantsStarted Apr 2015

Tampa, Florida, United States • Tampa, Florida, United States • Tampa, Florida, United States +6 more locations

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer

Find Trials by Condition in Maryland

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Phase 2B Safety and Efficacy Study of VGT-309 in Subjects With Cancer in the Lung.

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

Horizon Two Adaptive Platform Study in High Risk Newly Diagnosed Multiple Myeloma

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD).