Clinical Trials in Maryland

Showing 22121-22140 of 23,284 trials

Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain

NCT00404417

This study will assess the efficacy and the duration of efficacy of Botulinum toxin A (Botox®) injected into the lumbar paraspinal muscles for reducing pain and disability in subjects suffering from chronic low back pain of six months duration or longer and arising from an identifiable muscle strain injury or back trauma. The treatment modality and techniques used are based on a successful prior 4 month open-labeled pilot study done by this research group, but will employ a prospective double-blind, randomized, cross-over design to control for any placebo or mechanical trigger-point injection effects. Subjects will also be assessed for a longer duration to better define the duration of efficacy.

Chronic Low Back Pain

Walter Reed Army Medical Center160 participantsStarted Mar 2007

Washington D.C., District of Columbia, United States

TERMINATEDPhase 117 miles

Study of BMS-582664 in Combination With Either FOLFIRI or FOLFOX for Gastrointestinal (GI) Malignancies

NCT00300027

The purpose of this study is to define the recommended dose of BMS-582664 that could be safely combined with 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) or 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) chemotherapy regimens in patients with advanced gastrointestinal malignancies and to evaluate the safety profile, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of these combinations.

Gastrointestinal Neoplasms

Bristol-Myers Squibb50 participantsStarted Apr 2006

Little Rock, Arkansas, United States • Los Angeles, California, United States • Washington D.C., District of Columbia, United States +3 more locations

Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain

Study of BMS-582664 in Combination With Either FOLFIRI or FOLFOX for Gastrointestinal (GI) Malignancies

Find Trials by Condition in Maryland

Safety Study of Depakote Versus Lithium in African Americans With Bipolar Disorder

Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy

Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia

A Randomized, Placebo-Controlled Trial of BMS-275291 Given Daily for 12 Months to Women With Stage 1c-IIIA Breast Cancer Receiving Adjuvant Chemotherapy and/or Hormonal Therapy

Diabetes Control and Complications Trial (DCCT)

Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Anterior Pituitary Function in Patients With Hydrocephalus

Study of XL999 in Patients With Previously Treated Ovarian Cancer

Randomized Study of Human-Milk Based Nutrition Versus Formula in Premature Infants

Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors

Bryostatin 1 and Cytarabine in Treating Patients With Relapsed Acute Myelogenous Leukemia

Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma

Bryostatin 1 and High Dose Cytarabine in Treating Patients With Refractory or Relapsed Leukemia or Lymphoma

Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain

Extended Management and Measurement of Autism

Preimplantation Genetic Diagnosis for the Indication of Advanced Reproductive Age

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

Safety Study of XL999 in Adults With Non-Small-Cell Lung Cancer