Clinical Trials in Los Angeles

Showing 7781-7800 of 16,901 trials

Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

NCT02553941

This phase Ib trial studies the side effects and best dose of ibrutinib when given together with azacitidine in treating patients with myelodysplastic syndrome that is likely to occur or spread (higher risk) and who were previously treated or untreated and unfit for or refused intense therapy. Ibrutinib and azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Chronic Myelomonocytic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+2 more

Brian Jonas21 participantsStarted May 2016

Los Angeles, California, United States • Orange, California, United States • Sacramento, California, United States +2 more locations

COMPLETEDPhase 3< 1 mile

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration

NCT03677934

Study GR40548 is a Phase III, randomized, multicenter, open-label (visual assessor \[VA\]-masked), active-comparator study designed to assess the efficacy, safety, and pharmacokinetics (PK) of 100mg/ml delivered via the Port Delivery System with ranibizumab (PDS) compared with ranibizumab intravitreal injections at 0.5 mg (10 mg/mL) in participants with neovascular age-related macular degeneration (nAMD).

Neovascular Age-Related Macular Degeneration

Hoffmann-La Roche415 participantsStarted Sep 2018

Mesa, Arizona, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +74 more locations

Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration

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Randomized Trial of a Social Networks Intervention

Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma

TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy

Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa

A Mind-Body Intervention for Chemotherapy-Induced Peripheral Neuropathy

A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD5462 Following Single and Multiple Ascending Dose Administration to Healthy Volunteers

Dysport® Adult Lower Limb Spasticity Study

(VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST

Near-Infrared Laser Stimulation for Various Neurological Conditions

Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test?

Phase 1 Oral QPX7831 SAD and MAD in Healthy Adults

Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee

A Phase 2 Influenza A Challenge Study Following Oral Administration of an H1N1 HA Ad-Vector Seasonal Flu Vaccine

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced Solid Tumors

A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation

Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used