Clinical Trials in Los Angeles

Showing 5661-5680 of 16,901 trials

Effects of Biofeedback on Somatic Symptoms

NCT05120648

Biofeedback is a therapeutic paradigm that teaches patients how to gain awareness and control over previously unrecognized sympathetic changes such as body temperature, blood pressure, and heart rate. We propose to use a six session biofeedback protocol that includes heart-rate variability (HRV) biofeedback, respiration/relaxation training, and body temperature control to treat UCLA patients with chronic medical conditions (e.g. pulmonary, neurology) and somatic symptoms (pain, psychosomatic non-epileptic seizures, panic attacks, long-COVID symptoms). The aim of the study is to determine whether patients who complete a six-session biofeedback protocol report a decrease in somatic symptoms, and improvements in self-rated mental health (depression, anxiety, quality of life) after the program and at three-months follow-up. The investigators will also study whether these improvements are also related to reduced healthcare utilization.

Somatic Symptom

University of California, Los Angeles20 participantsStarted Sep 2021

Los Angeles, California, United States

COMPLETEDPhase 3< 1 mile

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

NCT05033080

The purpose of this study evaluates the efficacy and safety of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants who were heterozygous for F508del and a minimal function mutation (F/MF participants).

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated435 participantsStarted Sep 2021

Birmingham, Alabama, United States • Tucson, Arizona, United States • Little Rock, Arkansas, United States +136 more locations

Effects of Biofeedback on Somatic Symptoms

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Find Trials by Condition in Los Angeles

Optimizing Outcomes of Treatment-Resistant Depression in Older Adults

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With Other Antiretroviral Agents in People Living With HIV

Evaluation of a Diagnostic Device for Detection of Nasal Staphylococcus Aureus

Near Patient Molecular Testing in Sepsis

SMR Stemless Reverse Vs SMR Reverse Shoulder System

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

A Study to Learn About The Study Medicine (PF-07038124) In Patients With Mild To Moderate Atopic Dermatitis Or Mild To Severe Plaque Psoriasis.

Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment

A Study of MK-1167 in Healthy Elderly Participants (MK-1167-004)

Safety, Tolerability, and Pharmacokinetics Study of MK-8189 in Participants With Schizophrenia and Healthy Participants (MK-8189-011)

Assessment of the Safety and Effectiveness of a Micro-RF Skin Treatment Device (nebulyft）

Health in Motion Pragmatic Clinical Trial - WRAPAROUND

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors

Observational Study of Obstructive Lung Disease (NOVELTY)

WHOOP ECG Software Performance Assessment Study

The MOTION Study - Treatment of LSS With the MILD Procedure

A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry