Clinical Trials in Los Angeles

Showing 5601-5620 of 16,901 trials

First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer

NCT05159440

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-MAB in patients with advanced cancer

Advanced Solid TumorGastric CancerPancreas Cancer+1 more

TORL Biotherapeutics, LLC70 participantsStarted Jan 2022

Fullerton, California, United States • Los Angeles, California, United States • Torrance, California, United States +5 more locations

COMPLETEDPhase 1/2< 1 mile

Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.

NCT03345485

Tinostamustine (EDO-S101) is a first-in-class alkylating deacetylase inhibitor designed to improve drug access to deoxyribonucleic acid (DNA) strands, induce DNA damage and counteract its repair in cancer cells. The main purpose of this study is to assess the safety, tolerability and efficacy of Tinostamustine in subjects with advanced solid tumours. Subjects will be given Tinostamustine via intravenous infusion on Days 1 and 15 of a 4-week cycle, the dose and infusion time will vary depending on the phase of the study.

Small Cell Lung CancerSoft Tissue SarcomaTriple-negative Breast Cancer+2 more

Mundipharma Research Limited71 participantsStarted Nov 2017

Los Angeles, California, United States • Palo Alto, California, United States • Ann Arbor, Michigan, United States +10 more locations

First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer

Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.

Find Trials by Condition in Los Angeles

Assessment of Macrophage Activation syndromE in STill's Disease

Stockholm3 Validation Study in a Multi-Ethnic Cohort

Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

An Evaluation of a Cytomegalovirus (CMV) Vaccine (ASP0113) in CMV-Seropositive and CMV-Seronegative Healthy Subjects and CMV-Seronegative Dialysis Patients

QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer

A Mobile Phone Based Pilot Intervention to Prevent Obesity in Latino Preschool Children

Assess Aesthetic Improvement and Onset of QM1114-DP in Subjects With Moderate to Severe Glabellar Lines

Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

Study of Monovalent and Bivalent Recombinant Protein Vaccines Against COVID-19 in Adults 18 Years of Age and Older

Study to Learn How Different Forms of The Study Medicine Called Danuglipron Are Taken up Into the Blood In Healthy Adults

Vogelxo(R) ABPM Study in Hypogandal Men

A Study to Investigate the Effect of Renal Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Renal Function

Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

Milademetan in Advanced/Metastatic Solid Tumors

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty

Evaluation of Safety and Effectiveness of the Essure (Model ESS505) Device to Prevent Pregnancy in Women

SL-401 as Consolidation Therapy in Patients With Adverse Risk Acute Myeloid Leukemia in First Complete Remission