Clinical Trials in Los Angeles

Showing 4461-4480 of 12,794 trials

Trial of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma

NCT03077685

Open-label, dose-escalating, Phase IIa trial of NanoPac® to treat subjects with locally advanced pancreatic adenocarcinoma via direct intratumoral injection.

Locally Advanced Pancreatic Adenocarcinoma

NanOlogy, LLC54 participantsStarted Dec 2017

Los Angeles, California, United States • Fort Wayne, Indiana, United States • El Paso, Texas, United States +1 more locations

RECRUITINGPhase 3< 1 mile

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

NCT06095583

The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use of toripalimab alone or in combination with tifcemalimab as consolidation therapy in patients with limited-stage small cell lung cancer without disease progression following chemoradiotherapy. Tifcemalimab is a monoclonal antibody against B and T lymphocyte attenuator (BTLA). Toripalimab is a monoclonal antibody against programmed death protein-1 (PD-1). Neither drug is approved for treatment of This combination regimen is investigational in limited stage-small cell lung cancer in any country.

Limited-stage Small Cell Lung Cancer (LS-SCLC)

Shanghai Junshi Bioscience Co., Ltd.756 participantsStarted Nov 2023

Goodyear, Arizona, United States • Tucson, Arizona, United States • Hot Springs, Arkansas, United States +153 more locations

Trial of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Find Trials by Condition in Los Angeles

A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis Pigmentosa

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Open-Label Study of Oral Treprostinil in Digital Ulcers

Expanded Access Protocol of Teprotumumab (HZN-001) for Patients With Active Thyroid Eye Disease

A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers

Proof of Concept Study of Rilzabrutinib in Adult Patients With Moderate-to-severe Atopic Dermatitis

Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA

Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer

Treatment of Tendinosis Using the TenJet Hydroresection System

An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia

Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria