Clinical Trials in Illinois

Showing 8761-8780 of 14,943 trials

A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer

NCT01649336

This is a Phase 1 study during which patients with platinum-resistant epithelial ovarian, fallopian tube or primary peritoneal cancer will receive investigational study drug MEK162 and paclitaxel. Patients will receive increasing doses of study drug in combination with paclitaxel in order to achieve the highest dose of study drug possible that will not cause unacceptable side effects. Patients will be followed to see what side effects the combination causes and what effectiveness the combination has, if any, in treating the cancer. Approximately 36 patients from the US will be enrolled in this study.

Epithelial Ovarian CancerFallopian Tube CancerPeritoneal Cancer

Array Biopharma, now a wholly owned subsidiary of Pfizer36 participantsStarted Jul 2012

Scottsdale, Arizona, United States • Lafayette, Indiana, United States • New York, New York, United States +1 more locations

TERMINATEDPhase 2121 miles

Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT)

NCT03298412

The study will estimate the MRD-negative response rate after treatment with blinatumomab in subjects with high-risk DLBCL who are MRD-positive following aHSCT. The clinical hypothesis is that the MRD-negative response rate will be greater than 10%. Achieving an MRD-negative response rate of 30% would be of scientific and clinical interest.

High-risk Diffuse Large B-cell Lymphoma

Amgen10 participantsStarted May 2018

Atlanta, Georgia, United States • Maywood, Illinois, United States • Cleveland, Ohio, United States +29 more locations

A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer

Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT)

Find Trials by Condition in Illinois

Behavioral Therapy Of Obstetric Sphincter Tears

A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke

Vaccine Therapy in Treating Patients With Persistent or Recurrent Cervical Cancer

Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture

Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma

Randomized Evaluation of Default Access to Palliative Services

Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer

Dose Finding Study to Treat High Phosphate Levels in the Blood.

Safety and Efficacy Study of Single Weekly Bortezomib in Newly Diagnosed Multiple Myeloma

Radiofrequency Ablation in Treating Patients With Liver Cancer and Cirrhosis

Renal AL Amyloid Involvement and NEOD001

A Study of Vantictumab (OMP-18R5) in Combination With Docetaxel in Patients With Previously Treated NSCLC

Oral Iron for Erythropoietic Protoporphyrias

A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian

Clinical Evaluation of Flortaucipir F 18

Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations