Clinical Trials in Illinois

Showing 5061-5080 of 19,692 trials

ALT-801 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus (T2DM)

NCT05134662

This is a Phase 1, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety and tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of ALT-801 and its effects on glucose control in overweight and obese subjects with type 2 diabetes mellitus (T2DM).

Type 2 Diabetes

Altimmune, Inc.55 participantsStarted Feb 2022

Fort Myers, Florida, United States • Sarasota, Florida, United States • River Forest, Illinois, United States +4 more locations

Active Not RecruitingPhase 3125 miles

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain

NCT05037123

The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain. Participants randomized to the first arm will receive a 0.35 mg/kg dose after induction, followed by a 0.25 mg/kg/hr infusion during surgery (up to a maximum of 6 hours) and continued for 2 hours postoperatively. Participants in the second arm will receive a single dose of 0.6 mg/kg of ketamine in the post-anesthesia care unit, and the final group will serve as the control group and receive saline (no ketamine).

Chronic Postsurgical Pain

NYU Langone Health765 participantsStarted Jan 2022

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Chicago, Illinois, United States +11 more locations

ALT-801 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus (T2DM)

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain

Find Trials by Condition in Illinois

COVID Protection After Transplant - Sanofi GSK (CPAT-SG) Study

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain

Post-Approval Study of the TREO Abdominal Stent-Graft System

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy

Clinical Investigation of the Next-Generation Intraocular Lenses

DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

Effect of Ketamine and Etomidate During RSI on Long Term Outcomes

A Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME)

A Study Evaluating Efficacy and Safety of VX-993 for Acute Pain After a Bunionectomy

International Rare Histiocytic Disorders Registry (IRHDR)

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

Implementing Precision Medicine in cOmmunity HospiTALs