Clinical Trials in Houston

Showing 17561-17580 of 17,885 trials

MSX-122 Administered Orally in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

NCT00591682

Primary Objectives: 1. To determine the maximum tolerated dose (MTD) and the recommended Phase II dose(s) and schedule of MSX-122 2. To characterize the dose limiting toxicities (DLTs) and determine the overall safety and tolerability of MSX-122 Secondary Objectives: 1. To determine the pharmacokinetics and pharmacodynamics of orally administered MSX-122 2. To evaluate the preliminary evidence for anti-tumor activity of MSX-122 3. To perform correlative studies to elucidate signaling pathways involved in CXCR4 activation in blood and optional tissue specimens by IHC (immunohistochemistry) and RPPA (reverse phase protein microarrays)

Solid Tumors

Metastatix, Inc.27 participantsStarted Nov 2007

Houston, Texas, United States

COMPLETEDNA< 1 mile

Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)

NCT00153634

This was a randomized multi-center clinical trial to compare the microbiological efficacy, clinical efficacy, and safety of using standard versus biofilm susceptibility testing of P. aeruginosa sputum isolates to guide antibiotic selection for treatment of airway infection in clinically stable patients with CF.

Cystic FibrosisChronic Bronchitis

Seattle Children's Hospital75 participantsStarted Mar 2004

Iowa City, Iowa, United States • St Louis, Missouri, United States • Cincinnati, Ohio, United States +5 more locations

MSX-122 Administered Orally in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)

Find Trials by Condition in Houston

Safety and Pharmacokinetics Study in VLBW Neonates With BSYX-A110

Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy

Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients

A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis

Genetics of Ankylosing Spondylitis

A Study to Assess the Long-Term Safety of Tacrolimus Cream in the Treatment of Psoriasis

Safety and Efficacy Study of AV608 in Subjects With Social Anxiety Disorder

A Prospective, Randomized, Parallel Crossover Study Demonstrating Subject Wearability and Usability of the I-Port Injection Port

NGX-4010 for the Treatment of Postherpetic Neuralgia

Pharmacogenomics Blood Sampling Protocol For Irinotecan/Fluorouracil/Leucovorin(CPT-11/FU/LV).

GALLEX 1 - Long Term Extension Study in Patients With Type 2 Diabetes

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

A Phase IIIB Study to Compare the Efficacy and Safety of Concomitant Treatment in Patients With COPD

A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism

The Atrial High Rate Episodes in Pacemaker Patients

Huperzine A in Alzheimer's Disease

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Clarithromycin Extended Release for the Treatment of Pneumonia in Adult Patients

GALLANT 4 Tesaglitazar vs. Glibenclamide