Clinical Trials in Houston

Showing 1681-1700 of 15,366 trials

A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors

NCT07123103

The primary purpose of the study is to characterize the safety and tolerability of XB371. The dose-escalation cohorts and Part B of the expansion cohorts are non-randomized. Part A of the expansion cohorts is randomized.

Solid Tumors

Exelixis150 participantsStarted Aug 2025

Rogers, Arkansas, United States • Los Angeles, California, United States • Washington D.C., District of Columbia, United States +6 more locations

Active Not RecruitingPhase 1/2< 1 mile

Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)

NCT05882734

This is an Open-label, multicenter clinical study conducted in two Phases to establish the efficacy, safety, tolerability, and pharmacokinetics of the ataxia telangiectasia mutated and Rad3-related protein kinase (ATR) inhibitor Tuvusertib in Combination with Cemiplimab in Participants with Non-Squamous Non-Small Cell Lung Cancer (nsqNSCLC) that has Progressed on Prior Anti-PD-(L)1 and Platinum-based Therapies..

Non-Small Cell Lung Cancer

EMD Serono Research & Development Institute, Inc.61 participantsStarted Sep 2023

Santa Monica, California, United States • Pittsburgh, Pennsylvania, United States • Knoxville, Tennessee, United States +51 more locations

A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors

Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)

Find Trials by Condition in Houston

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma

A Study of Oral Oteseconazole (VT-1161) for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)

A Study to See Iftolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old withAutosomal Recessive Polycystic Kidney Disease (ARPKD)

Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Expanded Access Program of Zidesamtinib (NVL-520) for Patients With Advanced ROS1+ NSCLC or Other ROS1+ Solid Tumors

Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency