Clinical Trials in Houston

Showing 16961-16980 of 17,885 trials

A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.

NCT00040677

ICA-17043 is being developed for the chronic treatment of patients with sickle cell disease (SCD) in both adults and children. ICA-17043 is a potent and specific inhibitor of a channel in human red blood cells (RBCs) that blocks RBC dehydration. ICA-17043 is expected to inhibit RBC dehydration and thus should prevent or delay the sickling process. By reducing sickled cells, an improvement in anemia, a reduction in painful crises, and ultimately, less end-organ disease is anticipated.

Sickle Cell DiseaseSickle Cell Anemia

Icagen90 participantsStarted Feb 2002

Birmingham, Alabama, United States • Oakland, California, United States • San Francisco, California, United States +16 more locations

COMPLETEDPhase 3< 1 mile

Evaluation of Diagnostic HIV Ag/Ab Combo Assay

NCT00933933

To test blood specimens using a new investigational test that detects antigen and antibody to human immunodeficiency virus (HIV). Results will be compared to an approved HIV antibody test and supplemental testing performed to determine HIV status.

Human Immunodeficiency Viruses

Abbott Diagnostics Division635 participantsStarted Jun 2009

Phoenix, Arizona, United States • St. Petersburg, Florida, United States • Springfield, Illinois, United States +10 more locations

A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.

Evaluation of Diagnostic HIV Ag/Ab Combo Assay

Find Trials by Condition in Houston

Phase II Trial of Allovectin-7® for Metastatic Melanoma

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

FinESS Registry Study

Study of IMC-3G3 in Patients With Tumors That Are Not Responding to Standard Therapies or No Therapy is Available

Comparison of New Combination Inhaler (FlutiForm HFA MDI 100/10 µg) Versus Fluticasone and Formoterol Administered Alone, and Placebo, in Patients With Asthma

Evaluation of the Accuracy of the INRatio Prothrombin Time (PT) Monitoring System With a New Test Strip for the Oral Anticoagulation Therapy Patient in the Presence of Heparin and Low Molecular Weight Heparin (e.g., Enoxaparin or Dalteparin)

A Prospective Study to Evaluate the Safety of a New Monovalent Intranasal Influenza Vaccine

Electrophysiologic and Morphologic Assessment of the Substrate to Guide Implantation of Defibrillators in Dilated Cardiomyopathy

Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease

Double-Blind, Multicenter, Study Comparing the Efficacy and Safety of OMS103HP With Vehicle Irrigation Solution in Subjects Undergoing Meniscectomy

A Multiple Myeloma Trial in Patients With Bone Metastases

A Study for Patients With Type 2 Diabetes Mellitus

A Study of Nimotuzumab in Combination With External Radiotherapy in Non-Small Cell Lung Cancer

International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430

Back Pain in Patients With Severe Osteoporosis