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Clinical Trials in Houston | 17,885 Studies Near You | Clareo Health

Clinical Trials LocationsHouston

Clinical Trials in Houston

Discover 17,885 clinical trials near Houston, Texas. Find research studies in your area.

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Showing 16261-16280 of 17,885 trials

COMPLETEDPhase 2< 1 mile

A Study of NP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS)

NCT01281631

This is a Phase 2 randomized, double-blind, placebo-controlled, multicenter study of NP001 in subjects with ALS.

Amyotrophic Lateral Sclerosis

Neuraltus Pharmaceuticals, Inc.136 participantsStarted Feb 2011

Scottsdale, Arizona, United States • Irvine, California, United States • Los Angeles, California, United States +14 more locations

COMPLETEDPhase 3< 1 mile

Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

NCT00671879

The purpose of this study is to determine if two sustained released formulations of carisoprodol are more effective than placebo.

Lower Back Pain

Meda Pharmaceuticals830 participantsStarted Apr 2008

Birmingham, Alabama, United States • Gulf Shores, Alabama, United States • Hueytown, Alabama, United States +70 more locations

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Breast Cancerin Houston Lung Cancerin Houston Prostate Cancerin Houston Colorectal Cancerin Houston Melanomain Houston Leukemiain Houston Lymphomain Houston Pancreatic Cancerin Houston Ovarian Cancerin Houston Brain Cancerin Houston Diabetes

Data from ClinicalTrials.govTerms

COMPLETEDPhase 3< 1 mile

Ramelteon in Adults With Chronic Insomnia

NCT00671567

The purpose of this study is to determine the safety and efficacy of Ramelteon, once daily (QD), in adult subjects with chronic insomnia.

Chronic Insomnia

Takeda848 participantsStarted Dec 2002

Birmingham, Alabama, United States • Mobile, Alabama, United States • Mesa, Arizona, United States +67 more locations

TERMINATEDPhase 2< 1 mile

A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.

NCT01288079

The purpose of this study is to assess the safety and effect of TC-5214 as a single therapy in patients with major depressive disorder who exhibit inadequate response to antidepressants.

Major Depressive Disorder

AstraZeneca145 participantsStarted Feb 2011

Beverly Hills, California, United States • Chino, California, United States • Garden Grove, California, United States +60 more locations

COMPLETEDPhase 3< 1 mile

A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder

NCT00542685

This study will evaluate the efficacy and safety of PD 0332334 for the treatment of generalized anxiety disorder.

Generalized Anxiety Disorder

Pfizer551 participantsStarted Oct 2007

Beverly Hills, California, United States • Encino, California, United States • National City, California, United States +40 more locations

TERMINATEDPhase 3< 1 mile

A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (2)

NCT00658372

This is a 10-week trial that evaluates the efficacy and safety of PD 0332334 in subjects, ages 18 to 65, with generalized anxiety disorder.

Generalized Anxiety Disorder

Pfizer360 participantsStarted May 2008

Arcadia, California, United States • Costa Mesa, California, United States • Escondido, California, United States +30 more locations

COMPLETEDPhase 2< 1 mile

A Phase 2 Study With IPI-926 in Patients With Myelofibrosis

NCT01371617

The purpose of this study is to determine the safety and efficacy of IPI-926 in patients with myelofibrosis (MF) (primary myelofibrosis \[PMF\], post-polycythemia vera myelofibrosis \[post-PV MF\], or post-essential thrombocythemia myelofibrosis \[post-ET MF\]).

Primary MyelofibrosisFibrosis, Bone Marrow

Infinity Pharmaceuticals, Inc.14 participantsStarted Oct 2011

Scottsdale, Arizona, United States • Palo Alto, California, United States • Houston, Texas, United States

COMPLETED< 1 mile

An Observational Study to Assess Respiratory Syncytial Virus (RSV) Respiratory Events Among Premature Infants

NCT00983606

The primary objective is to assess the burden of respiratory disease in outpatient settings among 32 to 35 weeks' gestational age (wGA) infants in the USA who did not receive RSV prophylaxis during the infants' first RSV season.

MedImmune LLC3,000 participantsStarted Sep 2009

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Dothan, Alabama, United States +219 more locations

TERMINATEDPhase 1< 1 mile

Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine

NCT00074607

Subject's are being asked to take part in this study because he or she has a type of cancer that has spread to the meninges (tissues that cover the brain and spinal cord). There is no known effective treatment for this specific disease or the subject has received all of the treatments that are known to work for his or her specific disease without success. Currently, there is no other effective treatment for this type of cancer. The purposes of this study are: * to determine the highest dose of gemcitabine, an anti-cancer drug, that can safely be given directly into the spinal fluid of children and adults whose cancer no longer responds to standard treatment; * to find out what effects (good and bad) gemcitabine has when given directly into the cerebrospinal fluid (called intrathecal administration) in children and adults with neoplastic meningitis (cancer that has spread to the lining of the brain and spinal cord); * to determine if gemcitabine is beneficial to the patient; * to understand how gemcitabine is handled by the body after intrathecal administration.

MeningitisNeoplasms

Baylor College of Medicine10 participantsStarted Dec 2001

Bethesda, Maryland, United States • Pittsburgh, Pennsylvania, United States • Pittsburgh, Pennsylvania, United States +2 more locations

COMPLETEDPhase 4< 1 mile

Phase4/Symbicort® Versus Pulmicort Flexhaler® in African Americans

NCT00702325

To compare the efficacy of SYMBICORT® pMDI 160/4.5 μg x 2 actuations twice daily (bid) to that of budesonide inhalation powder DPI 180 μg x 2 inhalations bid, in African American(self-reported) subjects with inhaled corticosteroid (ICS) dependent asthma.

AstraZeneca311 participantsStarted Jun 2008

Pell City, Alabama, United States • Bentonville, Arkansas, United States • Hot Springs, Arkansas, United States +54 more locations

TERMINATEDPhase 350 miles

A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (1)

NCT00658008

This is a 10-week trial that evaluates the efficacy and safety of PD 0332334 in subjects, ages from 18 to 65, with generalized anxiety disorder.

Generalized Anxiety Disorder

Pfizer501 participantsStarted Apr 2008

Litchfield Park, Arizona, United States • Costa Mesa, California, United States • Pasadena, California, United States +49 more locations

COMPLETEDPhase 279 miles

A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight

NCT00542009

Study of whether the investigational drug CE-326,597 improves glucose control and results in body weight loss in patients with type 2 diabetes

Weight ManagementTreatment Of Obesity

Pfizer252 participantsStarted Dec 2007

Phoenix, Arizona, United States • Fresno, California, United States • National City, California, United States +51 more locations

COMPLETEDPhase 3146 miles

Study of Efficacy of Ramelteon in Adults With Chronic Insomnia

NCT00671125

The purpose of this study is to determine the safety and efficacy of Ramelteon, once daily (QD), in the treatment of chronic insomnia using polysomnography and subjective measures of sleep

Chronic Insomnia

Takeda405 participantsStarted Jan 2003

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Hot Springs, Arkansas, United States +22 more locations

COMPLETEDPhase 3189 miles

FS VH S/D 500 S-apr in Vascular Surgery

NCT00892957

The purpose of this study was to compare safety and efficacy of FS VH S/D 500 s-apr (FS) versus manual compression in prosthetic expanded polytetrafluoroethylene (ePTFE) graft placement.

Hemostasis in Participants Receiving Peripheral Vascular Expanded Polytetrafluoroethylene (ePTFE) Graft Prostheses

Baxter Healthcare Corporation176 participantsStarted Jul 2009

Birmingham, Alabama, United States • Tucson, Arizona, United States • Fresno, California, United States +19 more locations

COMPLETEDPhase 1189 miles

Safety, Tolerability, and Antiviral Activity of ANA598 in Patients With Genotype-1 Chronic HCV Infection

NCT00782353

The purpose of this study is to investigate the safety, tolerability, and antiviral activity of ANA598 in patients with genotype-1 chronic hepatitis C infection.

Chronic Hepatitis C

Hoffmann-La Roche35 participantsStarted Oct 2008

St Louis, Missouri, United States • New York, New York, United States • San Antonio, Texas, United States +1 more locations

COMPLETEDPhase 2413 miles

Evaluate Efficacy, Safety and Tolerability of AZD1656 as Add-on Treatment to Metformin in Type 2 Diabetes Mellitus (TD2M) Patients

NCT01020123

The primary aim is to evaluate Efficacy, Safety and Tolerability of AZD1656 as Add-on Treatment to Metformin in TD2M Patients

Type II Diabetes Mellitus

AstraZeneca530 participantsStarted Oct 2009

Temuco, Araucania, Chile • Brentwood, TN, Chile • Santiago, Chile +74 more locations

COMPLETEDPhase 1638 miles

Ascending Dose Study of the Safety and Tolerability of REGN728 in Healthy Volunteers

NCT01197391

This study will test the safety and tolerability (how the body reacts to the drug) of REGN728 compared with placebo (an inactive substance that contains no medicine) in healthy subjects. The study drug and placebo will be administered by subcutaneous injection (under the skin) at the clinic visit. There will be 14 clinic visits, which will include 4 overnight stays. Subjects will be monitored by the study staff for side effects and the body's response to the study drug. Vital signs (blood pressure, temperature, breathing and heart rate) will be checked, blood and urine samples will be collected at some or all visits.

Regeneron Pharmaceuticals48 participantsStarted Aug 2010

Miramar, Florida, United States • Overland Park, Kansas, United States

COMPLETED660 miles

Microculture Kinetic (MiCK) Apoptosis Test Results With Drug Treatment Results in Cancer Patients

NCT00901264

The purpose of this study is to correlate the results of the MICK assay with short- and long-term results of treatments in cancer patients and evaluate the role of the MiCK assay in guiding chemotherapy of cancer patients.

Pierian Biosciences300 participantsStarted Dec 2008

La Verne, California, United States • Tampa, Florida, United States • Brentwood, Tennessee, United States +8 more locations

COMPLETEDPhase 1723 miles

A Study to Assess the Safety and Tolerability of Single Ascending Doses of REGN1033(SAR391786)

NCT01507402

This is a randomized, double-blind, placebo-controlled, single ascending dose study to assess the safety and tolerability of Intravenous (IV) and Subcutaneous (SC) REGN1033(SAR391786) in healthy volunteers.

Healthy Volunteers

Regeneron Pharmaceuticals76 participantsStarted Jan 2012

Honolulu, Hawaii, United States • Evansville, Indiana, United States

COMPLETEDPhase 41288 miles

Evaluation of Efficacy and Safety of Symbicort® as an add-on Treatment to Spiriva® in Patients With Severe COPD.

NCT00496470

The purpose of this study is to investigate the effect of combined treatment with Symbicort and Spiriva, in terms of improvement of lung function, symptoms and inflammatory markers, in patients with severe COPD.

Chronic Obstructive Pulmonary Disease, COPD

AstraZeneca660 participantsStarted May 2007

Concord, New South Wales, Australia • Sydney, New South Wales, Australia • Auchenflower, Queensland, Australia +90 more locations

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