Clinical Trials in Houston

Showing 10061-10080 of 15,366 trials

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

NCT03127735

To determine the maximum tolerated and / or recommended Phase II dose of oral mutant IDH1 (mIDH1) inhibitor BAY1436032 and to characterize its safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical efficacy in patients with mIDH1-R132X advanced acute myeloid leukemia (AML)

Leukemia, Myeloid, Acute

Bayer27 participantsStarted Jun 2017

Buffalo, New York, United States • New York, New York, United States • The Bronx, New York, United States +10 more locations

COMPLETEDPhase 3< 1 mile

A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)

NCT01539512

This Phase 3, randomized, double-blind, placebo-controlled study is to evaluate the effect of idelalisib in combination with rituximab on the onset, magnitude, and duration of tumor control in participants previously treated for chronic lymphocytic leukemia (CLL). Eligible patients will be randomized with a 1:1 ratio into 1 of the 2 treatment arms to receive either idelalisib plus rituximab or placebo plus rituximab. Participants who are tolerating primary study therapy but experience definitive CLL progression are eligible to receive active idelalisib therapy in the extension study, GS-US-312-0117.

Chronic Lymphocytic Leukemia

Gilead Sciences220 participantsStarted Apr 2012

Huntsville, Alabama, United States • Tucson, Arizona, United States • La Jolla, California, United States +69 more locations

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)

Find Trials by Condition in Houston

Prospective Study of Colonoscopic Resection of Large Polyps and Flat Lesions

The Collection and Storage of Umbilical Cord Blood for Transplantation

A Study for Patients With Acute Leukemia

Data Collection of Normal Tissue Toxicity for Proton Therapy for Pediatrics

Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis

Obesity: Cancer Risk Among African Americans

Prognostic Molecular and Environmental Factors in High-Risk Colon Cancer Patients

Genetic Study of Chronic Lymphocytic Leukemia Families

A 6-month Clinical Study to Evaluate the Effect of a Digital Disease Management Tool in Patients With T2DM

Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty

Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder

A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors

A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.

A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy

Fenzian Asthma Multicenter Outcomes Study