Clinical Trials in Houston

Showing 8181-8200 of 17,885 trials

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx

NCT04083222

This study evaluated the effect of ISIS 757456 (IONIS-AGT-LRx) on plasma angiotensinogen (AGT) and systolic blood pressure (SBP) in uncontrolled hypertensive participants who were on two to three antihypertensive medications.

Hypertension

Ionis Pharmaceuticals, Inc.26 participantsStarted Nov 2019

Birmingham, Alabama, United States • Los Angeles, California, United States • Tustin, California, United States +6 more locations

COMPLETEDPhase 2< 1 mile

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH.

NCT04019561

A Phase 2 study with 4 treatment groups of two differing doses and matched placebos designed to evaluate the safety (including hepatic safety), tolerability and pharmacodynamic effects of two dose levels of MEDI0382 in obese subjects with non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH). The subjects will have biopsy-confirmed NAFLD/NASH with liver fibrosis stage F1, F2 or F3. Approximately 72 subjects will be randomized

Non-alcoholic Fatty Liver Disease (NAFLD)Non-alcoholic Steatohepatitis (NASH)

MedImmune LLC74 participantsStarted Sep 2019

Tucson, Arizona, United States • Canoga Park, California, United States • Chula Vista, California, United States +24 more locations

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH.

Find Trials by Condition in Houston

Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

Connecting Seniors to Care

Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects

Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission

Efficacy, Tolerability, and Safety of DFN-15

Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product

A Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease

Investigating Safety, Tolerability and Efficacy of AZD5363 When Combined With Paclitaxel in Breast Cancer Patients

A Phase 1 Study of the CD73 Inhibitor(HLX23) Alone in Participants With Solid Tumor

Online Multi-component Psychological Intervention for Depression, Anxiety and Well-being in 7 Countries

Metformin in Children With Relapsed or Refractory Solid Tumors

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia A

Medical Masks vs N95 Respirators for COVID-19

A Study of Long-Term Responders on Olaparib