Clinical Trials in Houston

Showing 8021-8040 of 17,885 trials

177Lutetium-DOTA-Octreotate Therapy in Somatostatin Receptor-Expressing Neuroendocrine Neoplasms

NCT01237457

This is a phase II treatment protocol evaluating 177Lu-DOTATATE therapy for somatostatin receptor-expressing cancers including, but not limited to, those arising from the neural crest and involving such organs as the lungs, breast, gastrointestinal tract, skin, and endocrine (examples: pheochromocytoma, medullary carcinoma of the thyroid, non-radioiodine avid differentiated thyroid cancer, melanoma, renal cell, Merkel cell, paraganglioma, small cell lung, Carcinoid, and pancreatic islet cell malignancies).

Neuroendocrine Tumors

Ebrahim S Delpassand143 participantsStarted Oct 2010

Houston, Texas, United States

COMPLETEDPhase 2< 1 mile

A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal

NCT02399813

This is a single arm Phase 2 study. Stage 1 and 2 of the study are monotherapy evaluations of ADXS11-001 in 31 and 24 participants, respectively with persistent/recurrent, loco-regional or metastatic squamous cell carcinoma (SCCA) of the anorectal canal that have received at least 1 regimen for the treatment of advanced disease.

Anal CancerRectal Cancer

Advaxis, Inc.36 participantsStarted Jun 2016

Duarte, California, United States • New Haven, Connecticut, United States • Indianapolis, Indiana, United States +7 more locations

COMPLETEDPhase 1< 1 mile

First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin

NCT03507452

The purpose of this study is to evaluate, in patients with tumors known to express the protein mesothelin, the following properties of BAY2287411 injection: * safety (to identify, assess, minimize, and appropriately manage the risks associated to the study drug) * tolerability (the degree to which side effects can be tolerated by your body) * maximum tolerated dose * pharmacokinetics (the effect of your body on the study drug) * anti-tumor activity * recommended dose for further clinical development

Advanced Recurrent Malignant Pleural Epithelioid MesotheliomaAdvanced Recurrent Malignant Peritoneal Epithelioid MesotheliomaAdvanced Recurrent Serous Ovarian Cancer+1 more

Bayer36 participantsStarted Jun 2018

Bethesda, Maryland, United States • Houston, Texas, United States • Helsinki, Finland +4 more locations

177Lutetium-DOTA-Octreotate Therapy in Somatostatin Receptor-Expressing Neuroendocrine Neoplasms

A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal

First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin

Find Trials by Condition in Houston

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

Genetic Data Collection in Adult Participants to Identify Genetic Variants of Known Importance in Non-alcoholic Steatohepatitis (NASH)

Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation in Subjects With Paroxysmal Atrial Fibrillation

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

A Prospective Clinical Study of Phenylketonuria (PKU)

A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma

Streamlining Trauma Research Evaluation With Advanced Measurement

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

A Study to Test if TEV-48574 is Effective in Relieving Asthma

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites

Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention

FREEDOM COVID-19 Anticoagulation Strategy

A Phase II Study in Patients With Moderate to Severe Active Crohn's Disease

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain