Clinical Trials in Houston

Showing 7321-7340 of 13,620 trials

Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.

NCT01439152

BAY94-9343 was an antibody-drug conjugate (ADC) directed against the cancer antigen mesothelin on tumor cells.

Bayer148 participantsStarted Sep 2011

New Haven, Connecticut, United States • Chicago, Illinois, United States • Bethesda, Maryland, United States +5 more locations

COMPLETEDPhase 2< 1 mile

Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)

NCT02177136

This was a phase 2, double-blind (DB), placebo-controlled trial in participants with primary sclerosing cholangitis to evaluate the effect of obeticholic acid on liver biochemistry, in particular, serum alkaline phosphatase; and, safety. The long-term safety extension (LTSE) phase was conducted to evaluate the safety, tolerability, and efficacy of long-term, open-label use of OCA in participants with PSC who had completed the DB phase of the study.

Primary Sclerosing Cholangitis (PSC)

Intercept Pharmaceuticals77 participantsStarted Feb 2015

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Sacramento, California, United States +33 more locations

Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.

Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)

Find Trials by Condition in Houston

A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia

A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Fentanyl for Breakthrough Pain in the Emergency Department

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

High Resolution Imaging for Early and Better Detection of Bladder Cancer

Dysport in Hallux Abducto Valgus (HAV) Phase IIa

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142

A Study of Elotuzumab in Combination With Pomalidomide and Low Dose Dexamethasone and Elotuzumab in Combination With Nivolumab in Patients With Multiple Myeloma Relapsed or Refractory to Prior Treatment With Lenalidomide.

ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease

Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Cardiac Surgery

Long Term Study of Canakinumab (ACZ885) in Patients With Gout