Clinical Trials in Houston

Showing 7161-7180 of 13,620 trials

Neoadjuvant TDM1 With Lapatinib and Abraxane Compared With Trastuzumab Plus Pertuzumab With Paclitaxel

NCT02073487

This is a randomized, open label Phase II neoadjuvant study comparing the efficacy and safety of trastuzumab emtansine (T-DM1) plus lapatinib (L)followed by abraxane (A) versus trastuzumab plus pertuzumab followed by paclitaxel in patients with HER2-overexpressing breast cancer.

Breast Cancer

The Methodist Hospital Research Institute32 participantsStarted Feb 2014

Houston, Texas, United States • Houston, Texas, United States • Sugar Land, Texas, United States

WITHDRAWNPhase 2< 1 mile

Adjunctive CB1 Agonist Nabilone in Inpatients With Active Suicidal Ideation

NCT04807829

Suicide is a major crisis worldwide with rates projected to continue to increase. There is currently a dearth of novel pharmacologic treatment options for suicide available on the market. The endocannabinoid system has been recently shown to be associated with mood disorders including suicidality. The aim of the study is to determine whether treatment with Nabilone is capable of reducing suicidal ideation in adults after 3 days.

Suicidal Ideation

The University of Texas Health Science Center, HoustonStarted Apr 2021

Houston, Texas, United States

TERMINATEDPhase 3< 1 mile

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

NCT02952586

This is a phase 3 randomized, placebo controlled study to evaluate the safety and anti-tumor activity of Avelumab in combination with standard of care chemoradiation (SoC CRT) versus SoC CRT alone in front-line treatment of patients with locally advanced head and neck cancer.

Squamous Cell Carcinoma of the Head and Neck

Pfizer697 participantsStarted Nov 2016

Fayetteville, Arkansas, United States • Rogers, Arkansas, United States • Springdale, Arkansas, United States +313 more locations

Neoadjuvant TDM1 With Lapatinib and Abraxane Compared With Trastuzumab Plus Pertuzumab With Paclitaxel

Adjunctive CB1 Agonist Nabilone in Inpatients With Active Suicidal Ideation

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

Find Trials by Condition in Houston

Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma

An Integrated Assessment of the Safety and Effectiveness of Bexagliflozin for the Management of Essential Hypertension

Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects

Dose Range Study of CD5789 in Acne Vulgaris

A Phase 1/2, Open-label, Dose Finding Study to Evaluate CC-122 in Combination With Ibrutinib and Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)

Validation Study of RETINA-AI Galaxy™, an Automated Diabetic Retinopathy Screening Device

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer

Response to Phenylketonuria to Tetrahydrobiopterin (BH4)

Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

A Study Evaluating Pertuzumab (Perjeta) Combined With Trastuzumab (Herceptin) and Standard Anthracycline-based Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced, Inflammatory, or Early-stage Breast Cancer

Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)

Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING Low Dose Study)