Clinical Trials in Houston

Showing 6821-6840 of 13,620 trials

Safety Study of Enoblituzumab (MGA271) in Combination With Ipilimumab in Refractory Cancer

NCT02381314

The purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Yervoy (ipilimumab) when given to patients with B7-H3-expressing melanoma, squamous cell carcinoma of the head and neck (SCCHN), non small cell lung cancer (NSCLC) and other B7-H3 expressing cancers. The study will also evaluate what is the best dose of enoblituzumab to use when given with ipilimumab. Assessments will also be done to see how the drug acts in the body (pharmacokinetics (PK), pharmacodynamics) and to evaluate potential anti-tumor activity of enoblituzumab in combination with ipilimumab.

MelanomaNon Small Cell Lung Cancer

MacroGenics24 participantsStarted Mar 2015

Los Angeles, California, United States • New Haven, Connecticut, United States • Miami Beach, Florida, United States +7 more locations

COMPLETEDPhase 3< 1 mile

An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

NCT03669588

A randomized, double-blind, placebo controlled, multicenter Phase 3 trial to evaluate the efficacy, safety, tolerability, quality of life and impact on normal daily activities of ARGX-113 in patients with gMG.

Generalized Myasthenia Gravis

argenx167 participantsStarted Aug 2018

Phoenix, Arizona, United States • Carlsbad, California, United States • Los Angeles, California, United States +63 more locations

Safety Study of Enoblituzumab (MGA271) in Combination With Ipilimumab in Refractory Cancer

An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

Find Trials by Condition in Houston

Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By Surgery

Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery

Topotecan and Gefitinib (Iressa) for Ovarian, Peritoneal, or Fallopian Tube Cancer

Study to Determine Safety and Dose of NJH395 in Non-breast HER2+ Advanced Cancer

The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation

On-Q Pump vs Epidural for Postoperative Pain Control in Children

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study

Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Safety Study of MGA271 in Refractory Cancer

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Feasibility of Telemedicine Medical Abortion

Phase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal Carcinoma