Clinical Trials in Houston

Showing 5601-5620 of 13,620 trials

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

NCT04171843

This is a Phase 1/2a, nonrandomized, open-label, parallel assignment, single-dose, dose-escalation, and dose-expansion study to evaluate the safety and clinical activity of PBCAR269A, with or without nirogacestat, in adults with r/r MM. Study subjects in Cohort A will receive PBCAR269A and study subjects in Cohort B will receive PBCAR269A and nirogacestat. At each dose level, study subjects in Cohort A and Cohort B will receive the same dose of PBCAR269A. In Cohort B, all study subjects will follow the same dosing regimen of nirogacestat. This study was terminated prior to beginning of Phase II due to lack of sufficient therapeutic effect

Relapsed/Refractory Multiple Myeloma

Precision BioSciences, Inc.48 participantsStarted Apr 2020

Duarte, California, United States • San Francisco, California, United States • Boston, Massachusetts, United States +2 more locations

TERMINATEDNA< 1 mile

Impact of Fever Prevention in Brain Injured Patients

NCT02996266

This study will assess the impact of fever prevention on fever burden and short- and long-term neurologic outcomes in brain injured patients. Half of the subjects will undergo fever prevention using a targeted temperature management system and half of the subjects will be treated for fever should it develop.

FeverIschemic StrokeIntracerebral Hemorrhage+1 more

C. R. Bard686 participantsStarted Jan 2017

Los Angeles, California, United States • Palo Alto, California, United States • Aurora, Colorado, United States +37 more locations

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

Impact of Fever Prevention in Brain Injured Patients

Find Trials by Condition in Houston

Bioaerosol Sampling Device (BSD) Clinical Study

Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders

Interactive Voice Response System in Advanced Cancer Patients

Pixantrone (BBR 2778) in Patients With Refractory Acute Myelogenous Leukemia (AML)

INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD

Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.

Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients

Subchondroplasty® Knee RCT

Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies

Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants

A Study Assessing the Safety and Effectiveness of IC2000 and SPY Fluorescence Imaging Systems (SPY-PHI) in the Visualization of Lymphatic Vessels and Identification of Lymph Nodes During Sentinel Lymph Node Biopsy in Subjects With Breast Cancer

A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination

Human Epilepsy Project 2: Resistant Focal Seizures Study

Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Multi-Center Pilot Study of truSculpt Device