Clinical Trials in Houston

Showing 5061-5080 of 13,620 trials

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

NCT04541108

This is a multi-center, open-label Phase 0 Master Protocol designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumor microenvironment (TME) when administered intratumorally in microdose quantities via the CIVO device in patients with surface accessible solid tumors for which there is a scheduled surgical intervention. CIVO stands for Comparative In Vivo Oncology. Multiple substudies will include specified investigational agents and combinations to be evaluated.

Solid Tumor

Presage Biosciences15 participantsStarted Jul 2021

Sacramento, California, United States • Atlanta, Georgia, United States • Shreveport, Louisiana, United States +9 more locations

UNKNOWNNA< 1 mile

DuraSorb® in Prosthetic Breast Reconstruction

NCT04646057

This study compares outcomes of prospective mesh-based breast reconstructions to historical control breast reconstructions with no mesh.

Breast Reconstruction

Surgical Innovation Associates, Inc.168 participantsStarted Jan 2021

Chicago, Illinois, United States • Chicago, Illinois, United States • Evanston, Illinois, United States +4 more locations

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

DuraSorb® in Prosthetic Breast Reconstruction

Find Trials by Condition in Houston

A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS)

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor

Study of Turning Point Therapeutics LM-302 in Patients With Advance Solid Tumors

Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

BI 894999 First in Human Dose Finding Study in Advanced Malignancies

A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis

Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age

Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)

Study Using Negative Pressure to Reduce Apnea

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIIB107 in Healthy Adult Participants

Letrozole for Lymphangioleiomyomatosis

A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis

Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's Contracture

Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma