Clinical Trials in Florida

Showing 1701-1720 of 6,120 trials

Measurements of CSF Shunts and Off-Shunt Locations With Wireless Thermal Anisotropy Measurement Devices

NCT06513572

This study collects data using non-invasive devices for assessing CSF shunt flow using thermal anisotropy measurements in a prospective study setting. The study will collect data to compare measurements from flowing shunts, non-flowing shunts, and off-shunt locations.

Hydrocephalus

Rhaeos, Inc.10 participantsStarted Jul 2024

Orange, California, United States • West Hollywood, California, United States • Tampa, Florida, United States +5 more locations

COMPLETEDPhase 1/249 miles

Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)

NCT04046224

This is the first in human treatment with ST-920, a recombinant AAV2/6 vector encoding the cDNA for human a-Gal A. The purpose of this study is to evaluate the safety and tolerability of ascending doses of ST-920. ST-920 aims to provide stable, long-term production of α-Gal A at therapeutic levels in subjects with Fabry disease. The constant production of α-Gal A in humans should, importantly, enable reduction and potentially clearance of Fabry disease substrates Gb3 and lyso-Gb3. On Day 1, patients will be infused intravenously with a single dose of ST-920 and followed for a period of 52 weeks.

Fabry Disease

Sangamo Therapeutics33 participantsStarted Jul 2019

Irvine, California, United States • Tampa, Florida, United States • Atlanta, Georgia, United States +15 more locations

Measurements of CSF Shunts and Off-Shunt Locations With Wireless Thermal Anisotropy Measurement Devices

Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)

Find Trials by Condition in Florida

STEM-Parkinson's Disease

Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

A Study of SEA-CD40 Given With Other Drugs in Cancers

The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions

Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

Adalimumab in JIA-associated Uveitis Stopping Trial

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

A Study of IMR-687 in Subjects With Sickle Cell Disease

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma