Clinical Trials in Detroit

Showing 14681-14700 of 19,719 trials

Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia

NCT01363297

The Phase 1 portion of this study will assess the safety, tolerability and efficacy at increasing dose levels of inotuzumab ozogamicin in subjects with CD22-positive relapsed or refractory adult acute lymphocytic leukemia (ALL) in order to select the recommended phase 2 dose (RP2D) and schedule. The Phase 2 portion of the study will evaluate the efficacy of inotuzumab ozogamicin as measured by hematologic remission rate (CR + CRi) in patients in second or later salvage status.

Acute Lymphocytic Leukemia

Pfizer72 participantsStarted Aug 2011

Duarte, California, United States • Palo Alto, California, United States • Palo Alto, California, United States +12 more locations

COMPLETEDPhase 3< 1 mile

Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease

NCT00025259

This randomized phase III trial is studying different chemotherapy regimens given with or without radiation therapy to compare how well they work in treating children with newly diagnosed Hodgkin's disease. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving the drugs in different combinations may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. It is not yet known if chemotherapy is more effective with or without additional chemotherapy and/or radiation therapy in treating Hodgkin's disease.

Childhood Lymphocyte-Depleted Classical Hodgkin LymphomaChildhood Mixed Cellularity Classical Hodgkin LymphomaChildhood Nodular Lymphocyte Predominant Hodgkin Lymphoma+5 more

Children's Oncology Group1,734 participantsStarted Sep 2002

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Little Rock, Arkansas, United States +172 more locations

Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia

Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease

Find Trials by Condition in Detroit

Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma

Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)

Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura

Progel Vascular Sealant

A 12-Week Study in Asthmatic Children Ages 6 to <12 Years, Investigating the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared With Budesonide pMDI 80 μg

Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Pediatrics Subjects

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Healing With Venlafaxine After Injury (HELP)

A Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder

Phase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung Cancer

3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection

Safety and Efficacy of Cariprazine for Bipolar I Disorder

Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms

Depression in Alzheimer's Disease-2

Safety, Tolerability and Efficacy of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism

Prolonging Remission in Depressed Elderly (PRIDE)

BD FlowSmart™ Subcutaneous Insulin Infusion Set User Preference and Claims Study