Clinical Trials in Detroit

Showing 1361-1380 of 9,449 trials

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

NCT05886920

This first-in-human (FIH) study aims to assess the safety, tolerability, pharmacokinetics, and recommended phase 2 dose (RP2D) of D3S-002 given orally daily for 21-day cycles in adult subjects with advanced solid tumors with mitogen-activated protein kinase (MAPK) pathway mutations.

Advanced Solid Tumors With MAPK Pathway Mutations

D3 Bio (Wuxi) Co., Ltd67 participantsStarted Jul 2023

Detroit, Michigan, United States • New York, New York, United States • Blacktown, New South Wales, Australia +7 more locations

Enrolling By InvitationNA< 1 mile

Implementation of Suicide Risk Models in Health Systems

NCT06060535

The goal of this clinical trial is to evaluate a suicide risk model in patients receiving behavioral health care treatment. The main question it aims to answer is: Does the implementation of the suicide risk model reduce suicide attempts? Researchers will compare the outcomes of patients identified by the model to those in a usual care group.

Suicide, AttemptedSuicide, Fatal

Kaiser Permanente394,000 participantsStarted Oct 2022

Detroit, Michigan, United States • Bloomington, Minnesota, United States • Portland, Oregon, United States

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

Implementation of Suicide Risk Models in Health Systems

Find Trials by Condition in Detroit

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

An Open-label, Single-arm Study to Evaluate Pharmacokinetics and Safety of Subcutaneous Sonelokimab in Adolescents With Moderate to Severe Hidradenitis Suppurativa (VELA-TEEN)

Adversity, Brain and Opioid Use Study

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

A Study of Zigakibart in Adults With IgA Nephropathy

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

VIRTUUS Children's Study

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

Ulixertinib in People With Histiocytic Neoplasms

UNITY VCS Vitreoretinal Surgery

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder