Clinical Trials in Detroit

Showing 11741-11760 of 16,931 trials

Usability of an AI for M923 in Subjects With Moderate to Severe RA

NCT02722044

The purpose of this study is to evaluate the usability of an auto-injector (AI) for the delivery of M923 in patients with rheumatoid arthritis (RA)

Rheumatoid Arthritis

Momenta Pharmaceuticals, Inc.33 participantsStarted Apr 2016

Detroit, Michigan, United States • Greensboro, North Carolina, United States • Oklahoma City, Oklahoma, United States +4 more locations

COMPLETEDPhase 1/2< 1 mile

Phase 1 and 2 Study of PX-866 and Cetuximab

NCT01252628

The purpose of this Phase 1/2 open-label study is to determine the safety and efficacy of a cetuximab and PX-866 combination treatment. In the Phase 1 part of the study, the dose of PX-866 to be given in combination with cetuximab will be determined in patients with incurable metastatic CRC or incurable progressive, recurrent or metastatic SCCHN. The Phase 2 part of the study is a randomized evaluation of the antitumor activity and safety of PX-866 in combination with cetuximab versus cetuximab alone in patients with either incurable metastatic CRC who have a history of progression or recurrence following prior irinotecan and oxaliplatin containing regimens or are intolerant of irinotecan (Group 1) or incurable progressive, recurrent or metastatic SCCHN (Group 2).

Incurable Metastatic Colorectal CarcinomaIncurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Cascadian Therapeutics Inc.178 participantsStarted Dec 2010

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Escondido, California, United States +37 more locations

Usability of an AI for M923 in Subjects With Moderate to Severe RA

Phase 1 and 2 Study of PX-866 and Cetuximab

Find Trials by Condition in Detroit

Neurostimulation for the Relief of Acute Bronchoconstriction

Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia

Behavioral & Nutritional Treatment to Help CF Preschoolers Grow

Aspirin as a Novel Anti-Inflammatory Modality in the Fontan Patients

Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic Fevers

PF-00489791 For The Treatment Of Raynaud's

Biomarkers in Patients With Previously Untreated Invasive Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Study to Assess Functionality, Reliability, and Performance of a Pre-filled Syringe With Benralizumab Administered at Home

Radiosurgery or Open Surgery for Epilepsy Trial

A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanced Cancers, Including Acute Myeloid Leukemia.

Vascular Inflammation in Psoriasis - Extension Study

Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease

Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System

DFD06 Cream vs Clobetasol Propionate Cream, 0.05% Hypothalamic- Pituitary-Adrenal (HPA) Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis

Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017

A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

The Impact of Vitamin D on Disease Activity in Crohn's Disease