Clinical Trials in Detroit

Showing 9721-9740 of 16,931 trials

Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

NCT01775735

The primary objective of this study is to evaluate the safety and efficacy of occipital nerve stimulation (ONS) using the Boston Scientific Corporation (BSC) Precision™ System in the management of intractable chronic migraine, when used in conjunction with anti-migraine medications.

Migraine Disorders

Boston Scientific Corporation28 participantsStarted Apr 2013

Valencia, California, United States • Chicago, Illinois, United States • Chicago, Illinois, United States +7 more locations

COMPLETEDPhase 1< 1 mile

Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors

NCT00765973

A multi-center, open-label, two-arm, dose-escalation study to establish the safety, tolerability, MTD, and schedule of TLI administered intravenously as a 30 minute infusion in adult subjects with advanced solid tumors that have relapsed, are refractory to standard therapy, or for whom there is no standard therapy available. The two dosing regimens to be evaluated are: * Arm A: TLI dose on Days 1 and 8 of a 21-day treatment cycle (Starting dose: 1 mg/m2) * Arm B: TLI dose on Day 1 of a 21-day treatment cycle (Starting dose: 2 mg/m2) When one of the two arms reaches MTD, all future subjects will then be enrolled in the remaining study arm until MTD of that arm is reached.

Small Cell Lung CancerOvarian CancerSolid Tumors

Spectrum Pharmaceuticals, Inc14 participantsStarted Nov 2008

Detroit, Michigan, United States • San Antonio, Texas, United States

Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors

Find Trials by Condition in Detroit

Safety and Efficacy of Switching From Dolutegravir and ABC/3TC or ABC/DTG/3TC to B/F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed

A Registry for Hereditary Cancer Risk Assessment and Genetic Testing

DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia

Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum

GreenLight XPS Laser System Retrospective Chart Review

Bone Mineral Density in Women With Uterine Fibroids or Endometriosis

Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant

The ConnectedCancerCare Pilot Study (CCC)

A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy

Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi

A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye

Quality of Life in Patients With Congenital Afibrinogenemia

Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery

Safety and Tolerability Study for Age-Related Macular Degeneration

To Document the Effectiveness of BoNT-A Injection in Adult Subjects With Upper Limb Spasticity Following Stroke