Clinical Trials in Detroit

Showing 901-920 of 19,719 trials

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

NCT06234631

The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflammation and other related symptoms, after knee replacement surgery. The information collected in this study is necessary to help understand whether CBD may be a useful medication before and/or after surgery. The study hypothesis is that CBD exerts opioid-sparing effects through anti-inflammatory, analgesic, and anxiolytic mechanisms.

Knee Replacement SurgeryOsteoarthritis, Knee

Chad Brummett380 participantsStarted Mar 2024

Ann Arbor, Michigan, United States • Detroit, Michigan, United States

COMPLETEDPhase 32.6 miles

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

NCT03412747

This is a study to compare the efficacy of bimekizumab versus adalimumab in the treatment of subjects with moderate to severe chronic plaque psoriasis (PSO).

Chronic Plaque PsoriasisModerate to Severe Plaque Psoriasis

UCB Biopharma SRL478 participantsStarted Jan 2018

Glendale, Arizona, United States • Los Angeles, California, United States • San Diego, California, United States +74 more locations

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Find Trials by Condition in Detroit

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

Ribociclib (LEE011) Rollover Study for Continued Access

Prediction Augmented Screening Initiative

MED-EL Remote Care Multi-Center Feasibility Study

A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine

A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy