Clinical Trials in Detroit

Showing 8641-8660 of 14,997 trials

Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients

NCT01897714

The study will explore escalating doses of melflufen in combination with dexamethasone in small groups of patients to find the maximum tolerated dose of melflufen. That dose will then be used to determine the efficacy and safety profile of melflufen in combination with dexamethasone in a larger group of patients.

Relapsed and/or Relapsed-refractory Multiple Myeloma

Oncopeptides AB75 participantsStarted Jul 2013

Boston, Massachusetts, United States • Detroit, Michigan, United States • Chapel Hill, North Carolina, United States +4 more locations

COMPLETEDPhase 2< 1 mile

Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches

NCT02785913

This phase II trial studies how well taselisib (GDC-0032) works in treating patients with stage IV squamous cell lung cancer that has come back after previous treatment. This is a sub-study that includes all screened patients positive for the phosphoinositide 3-kinase (PI3K) biomarker. PI3K can cause tumor cells to grow more quickly. Taselisib may decrease the activity of PI3K and may be able to shrink tumors.

Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma

SWOG Cancer Research Network31 participantsStarted Nov 2014

Birmingham, Alabama, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +1108 more locations

Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients

Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches

Find Trials by Condition in Detroit

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)

The Impact of Heartfulness Program on Loneliness in High School Students in the US

Influence of Mucosa Tissue Thickness on Marginal Bone Loss of Implants With Smooth Collars

Safety and Efficacy of OT-82 in Participants With Relapsed or Refractory Lymphoma

Loratadine for Improvement of Bone Pain in Patients With Chronic Granulocyte-Colony Stimulating Factor (G-CSF) Use

Radiation Therapy in Treating Patients With Stage II or Stage III Oropharyngeal Cancer

Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

A Phase 2, Study of Ficlatuzumab Plus Erlotinib vs. Placebo Plus Erlotinib in Subjects With Previously Untreated Metastatic, EGFR-mutated NSCLC and BDX004 Positive Label

Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device

The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias

Topical Rapamycin to Erase Angiofibromas in TSC

Type 1 Diabetes and the Brain in Children

Cholinesterase Inhibitor Discontinuation

Clinical Trial Evaluating Acutrak Headless Compression Screw Fixation of Medial Malleolus Fractures

Exploratory Study of Relationships Between Malodor and Urine Metabolomics