Clinical Trials in Detroit

Showing 8301-8320 of 14,997 trials

Grapiprant (ARY-007) and Pembrolizumab in Patients With Advanced or Metastatic Post-PD-1/L1 NSCLC Adenocarcinoma

NCT03696212

This study will be conducted in adult participants diagnosed with NSCLC who have been previously treated for a minimum of 12 weeks with any PD-1 or PD-L1 checkpoint inhibitor. This is a phase 1b/2, multi-center, open label study designed to assess safety and tolerability of grapiprant in combination with pembrolizumab, to determine the recommended phase 2 dose (RP2D) with pembrolizumab, and to evaluate disease response with grapiprant based on investigator assessments. Pharmacokinetics, pharmacodynamics and response biomarkers will also be assessed.

Non-small Cell Lung Cancer Adenocarcinoma

Arrys Therapeutics18 participantsStarted Jan 2019

Stanford, California, United States • Detroit, Michigan, United States • Grand Rapids, Michigan, United States +3 more locations

COMPLETEDPhase 4< 1 mile

Epiduo Pediatric Acne Study

NCT01138735

The purpose of this study is to evaluate the safety and efficacy of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% administered once daily for up to 12 weeks in subjects 9 to 11 years of age with acne vulgaris.

Acne

Galderma R&D285 participantsStarted Jun 2010

Birmingham, Alabama, United States • San Diego, California, United States • Santa Rosa, California, United States +22 more locations

Grapiprant (ARY-007) and Pembrolizumab in Patients With Advanced or Metastatic Post-PD-1/L1 NSCLC Adenocarcinoma

Epiduo Pediatric Acne Study

Find Trials by Condition in Detroit

Adapalene-Benzoy Peroxide (BPO) Gel in the Treatment of Acne Vulgaris as a 6-month Maintenance

A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma

Celebrex In Acute Gouty Arthritis Study

Phase 3 Papulopustular Rosacea Study

Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne

Venezuelan Equine Encephalitis Monovalent Virus-Like Particle Vaccine

Clinical Trial of BI 425809 Effect on Cognition and Functional Capacity in Schizophrenia

Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)

PK and PD Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis

Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)

A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma

Trial to Evaluate the Safety and Immunogenicity of a 20-Valent Pneumococcal Vaccine in Adults 65 Years of Age or Older With Prior Pneumococcal Vaccination

A Six Week Study Of The Pain Relieving Effects Of Celecoxib 200 Mg Twice Daily Compared To Tramadol 50 Mg Four Times Daily In Patients With Chronic Low Back Pain

Atorvastatin Three Year Pediatric Study

Safety of FMT: OpenBiome Outcomes and Longitudinal Follow-up (STOOL) for Recurrent Clostridium Difficile Infection

Hemodialysis Access Surveillance Evaluation Study

Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)