Clinical Trials in Detroit

Showing 7241-7260 of 19,719 trials

Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients

NCT04723706

For many patients with hematologic disorders and bone marrow failure, hematopoietic stem cell transplantation (HSCT) or cellular therapy (CART) offers a curative treatment option. Patients after SCT or CART have a variable period of immune deficiency in the post-treatment period. The response to vaccination may affect the outcome of the transplant patients. the immunogenicity of vaccines in this immunosuppressed population is uncertain and variable. HSCT and CAR-T recipients are in a COVID-19 high-risk group and conferring immunity by vaccination at the earliest effective timepoint is desirable. At present, the immunogenicity and efficacy of SARS-CoV-2 vaccines in immune-impaired patients including autologous and allogeneic HSCT recipients is unknown. Furthermore, the impact of GvHD and IST on SARS-CoV-2 vaccine immunogenicity is unknown. the investigators aim to evaluate the vaccination response to COVID vaccines after SCT and CART

Hematologic Disorders and Bone Marrow Failure, Hematopoietic Stem Cell Transplantation (HSCT) or Cellular Therapy (CART)

Henry Ford Health System33 participantsStarted Mar 2021

Detroit, Michigan, United States

COMPLETEDPhase 4< 1 mile

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

NCT00942968

The purpose of this study is to determine the long term tolerability and safety of dalteparin in subjects with cancer.

Cancer

Pfizer338 participantsStarted Jun 2009

Tucson, Arizona, United States • Pleasant Hill, California, United States • Torrance, California, United States +39 more locations

Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

Find Trials by Condition in Detroit

The Effect of Intrawound Vancomycin Powder in Spine Surgery

A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis

Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age

Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients

Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)

The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

Understanding Decision Making in the Intensive Care Unit: a National Study

Post Market Study of Parietene™ DS Composite Mesh in Ventral Hernia Repair

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Ecopipam Treatment of Tourette's Syndrome in Subjects 7-17 Years

PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma

Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis

Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology

Expanded Access Protocol: Repeated Administration of Nurown® (Autologous MSC-NTF Cells) for the Treatment of ALS

A Trial to Evaluate the Effect of Food on LEO 152020